Role of Biomarkers in Periprosthetic Joint Infections

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dc.authoridCaglar, Ceyhun/0000-0003-4286-7852
dc.authoridsimsek, mehmet emin/0000-0002-8081-0550
dc.authoridAkcaalan, Serhat/0000-0001-7350-6422
dc.contributor.authorAkcaalan, Serhat
dc.contributor.authorOzaslan, Halil Ibrahim
dc.contributor.authorCaglar, Ceyhun
dc.contributor.authorSimsek, Mehmet Emin
dc.contributor.authorCitak, Mustafa
dc.contributor.authorAkkaya, Mustafa
dc.date.accessioned2025-01-21T16:44:18Z
dc.date.available2025-01-21T16:44:18Z
dc.date.issued2022
dc.departmentKırıkkale Üniversitesi
dc.description.abstractPeriprosthetic joint infection (PJI) is one of the most serious complications after joint arthroplasty. The incidence rate of PJI after total joint replacement is 1-3%. Although there are different guidelines and diagnostic criteria used to diagnose PJI, diagnosing PJI is a highly difficult process for orthopedists. The current Musculoskeletal Infection Society (MSIS) criteria are widely used for the diagnosis of PJI. These criteria include results from blood/synovial fluid tests, physical examination, and histological and microbiological analyses of intra-operative samples. However, there is currently no blood or synovial test that can definitively diagnose PJI. To make a more effective diagnosis of PJI, a large number of studies have explored and continue to investigate biomarkers. This review aims to provide general information about serum and synovial markers used for the diagnosis of PJI that may be used to create a database to guide researchers in new studies.
dc.identifier.doi10.3390/diagnostics12122958
dc.identifier.issn2075-4418
dc.identifier.issue12
dc.identifier.pmid36552965
dc.identifier.urihttps://doi.org/10.3390/diagnostics12122958
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25416
dc.identifier.volume12
dc.identifier.wosWOS:000900626900001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherMdpi
dc.relation.ispartofDiagnostics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectperiprosthetic joint infection; biomarker; blood; synovial fluid
dc.titleRole of Biomarkers in Periprosthetic Joint Infections
dc.typeReview Article

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