Immunohistochemical distribution of glucagon -, insulin -, somatostatin -, gastrin-, and serotonin-containing cells in the pancreas of the Van cat

dc.contributor.authorKaraca, Turan
dc.contributor.authorKara, Adem
dc.contributor.authorŞimşek, Nejdet
dc.contributor.authorUslu, Sema
dc.contributor.authorTekiner, Deniz
dc.contributor.authorYörük, Mecit
dc.date.accessioned2021-01-14T18:16:17Z
dc.date.available2021-01-14T18:16:17Z
dc.date.issued2014
dc.description.abstractThe regional distribution, relative frequency, and appearance of glucagon (A-cell)-, insulin (B-cell)-, somatostatin (D-cell)-, gastrin (G-cell)-, and serotonin (EC-cell)-secreting cells in the endocrine and exocrine pancreas of Van cats were examined using the immunohistochemistry method. Glucagon immunopositive A-cells were principally found in the central region of the islets of Langerhans, while insulin immunopositive B-cells were located in the periphery of the pancreatic islets. Moreover, several A- and B-cells were observed as only single cells or clusters of 2 to 3 immunopositive cells in the exocrine parenchyma and the pancreatic duct epithelium. Somatostatin and gastrin immunopositive reactivities were negligible in the peripheral regions of the pancreatic islets of Langerhans and in the exocrine parenchyma. However, serotonin-immunopositive EC-cells were observed in neither the endocrine islets nor any other sites of the tissue. The existence, regional distribution, and relative frequency of A-, B-, D-, G- and EC-cells in the pancreas of Van cats have been analyzed in this study for the frst time. The immunopositivity and distribution of endocrine cells in the Van cat pancreas were determined to be partially diferent from those of other carnivorous species such as dogs and other cats.en_US
dc.identifier.citationKaraca T., Kara A., Şimşek N., Uslu S., Tekiner D., Yörük M. (2014). Immunohistochemical distribution of glucagon -, insulin -, somatostatin -, gastrin-, and serotonin-containing cells in the pancreas of the Van cat. Turkish Journal of Veterinary and Animal Sciences, 38(3), 304 - 311.en_US
dc.identifier.endpage311en_US
dc.identifier.issn1300-0128
dc.identifier.issn1303-6181
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-84922833412
dc.identifier.scopusqualityQ3
dc.identifier.startpage304en_US
dc.identifier.trdizinid165884
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TVRZMU9EZzBOQT09
dc.identifier.urihttps://hdl.handle.net/20.500.12587/13085
dc.identifier.volume38en_US
dc.identifier.wosWOS:000336891000013
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofTurkish Journal of Veterinary and Animal Sciences
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectZiraat Mühendisliğien_US
dc.titleImmunohistochemical distribution of glucagon -, insulin -, somatostatin -, gastrin-, and serotonin-containing cells in the pancreas of the Van caten_US
dc.typeArticle

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