Fabrication and characterization of gold-nanoparticles/chitosan film: a scaffold for L929-fibroblasts
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Tarih
2013
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Taylor & Francis Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The objective of the present study was to fabricate a gold nanoparticle crosslinked chitosan (Ch/AuNPs) composite film simple and to evaluate its use as a carrier matrix for L929-fibroblasts. L929-fibroblasts were seeded either onto Ch or Ch/AuNPs scaffolds. The Ch/AuNPs scaffold exhibited a higher cell proliferation and growth rate. The cytotoxicity test determined trypan blue staining indicated that Ch scaffolds devoid of AuNPs expressed almost no toxicity while the Ch/AuNPs composite scaffolds expressed a very limited toxicity only at higher doses. The Ch/AuNPs scaffold promotes cell attachment, growth and proliferation with almost no cytotoxicity.
Açıklama
Tamer, Ugur/0000-0001-9989-6123
Anahtar Kelimeler
chitosan, cytotoxicity, gold nanorod, L929-fibroblasts
Kaynak
Artificial Cells Nanomedicine And Biotechnology
WoS Q Değeri
Q4
Scopus Q Değeri
Q1
Cilt
41
Sayı
6
Künye
closedAccess
