Fabrication and characterization of gold-nanoparticles/chitosan film: a scaffold for L929-fibroblasts

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dc.contributor.authorTurk, Mustafa
dc.contributor.authorTamer, Ugur
dc.contributor.authorAlver, Erol
dc.contributor.authorCiftci, Hakan
dc.contributor.authorMetin, Aysegul U.
dc.contributor.authorKarahan, Siyami
dc.date.accessioned2020-06-25T18:06:54Z
dc.date.available2020-06-25T18:06:54Z
dc.date.issued2013
dc.departmentKırıkkale Üniversitesi
dc.descriptionTamer, Ugur/0000-0001-9989-6123
dc.description.abstractThe objective of the present study was to fabricate a gold nanoparticle crosslinked chitosan (Ch/AuNPs) composite film simple and to evaluate its use as a carrier matrix for L929-fibroblasts. L929-fibroblasts were seeded either onto Ch or Ch/AuNPs scaffolds. The Ch/AuNPs scaffold exhibited a higher cell proliferation and growth rate. The cytotoxicity test determined trypan blue staining indicated that Ch scaffolds devoid of AuNPs expressed almost no toxicity while the Ch/AuNPs composite scaffolds expressed a very limited toxicity only at higher doses. The Ch/AuNPs scaffold promotes cell attachment, growth and proliferation with almost no cytotoxicity.en_US
dc.description.sponsorshipKirikkale UniversityKirikkale University; [2012/127]en_US
dc.description.sponsorshipThe authors gratefully acknowledge the financial support from Kirikkale University. Research Fund through Grant No: 2012/127.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.3109/21691401.2012.761228
dc.identifier.endpage401en_US
dc.identifier.issn2169-1401
dc.identifier.issn2169-141X
dc.identifier.issue6en_US
dc.identifier.pmid23330692
dc.identifier.scopus2-s2.0-84889665603
dc.identifier.scopusqualityQ1
dc.identifier.startpage395en_US
dc.identifier.urihttps://doi.org/10.3109/21691401.2012.761228
dc.identifier.urihttps://hdl.handle.net/20.500.12587/5405
dc.identifier.volume41en_US
dc.identifier.wosWOS:000329843900007
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofArtificial Cells Nanomedicine And Biotechnology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectchitosanen_US
dc.subjectcytotoxicityen_US
dc.subjectgold nanoroden_US
dc.subjectL929-fibroblastsen_US
dc.titleFabrication and characterization of gold-nanoparticles/chitosan film: a scaffold for L929-fibroblastsen_US
dc.typeArticle

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