Possible predictive clinical and radiological markers in decision making for surgical intervention in patients with Chiari Malformation type 1

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dc.authoridBAKAR, BULENT/0000-0002-6236-7647
dc.authoridAKKAYA, SULEYMAN/0000-0003-0597-1861
dc.authoridAlhan, Aslihan/0000-0003-3945-9073
dc.contributor.authorYuksel, Ulas
dc.contributor.authorBurulday, Veysel
dc.contributor.authorAkkaya, Suleyman
dc.contributor.authorBaser, Selcuk
dc.contributor.authorOgden, Mustafa
dc.contributor.authorAlhan, Aslihan
dc.contributor.authorBakar, Bulent
dc.date.accessioned2025-01-21T16:43:30Z
dc.date.available2025-01-21T16:43:30Z
dc.date.issued2022
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackground The first aim of this study was to compare the clinical data and posterior fossa morphometry obtained during the admission to the hospital between control group individuals (who had not Chiari Malformation (CM) type 1) and CM type 1 patients treated surgically or not. The second aim was to create a valid and reliable scale that can predict the decision-making for surgical intervention simply and easily in these patients. Materials Medical data and radiological images of 70 CM type 1 patients during their admission to the hospital were compared with the data of 69 control group individuals. Results Conservative treatment and/or follow-up was applied to 58 (82.9%) patients, and 12 (17.1%) patients underwent surgery. ROC analysis showed that the presence of myelopathy, tonsillar herniation >8 mm, Chamberlain line >84 mm, McRae line >44.50 mm, and odontoid process-McRae line angle <10.50 degrees could be used as predictive markers in decision-making for surgical intervention (p < 0.05). Logistic Regression analysis revealed that symptoms severity, and McRae line value would be the 'best parameters' in decision-making for surgical intervention (p < 0.05). A scale named the CHIASURG scale developed using this study's parameters showed that the parameters of 'depth of tonsillar herniation', 'Chamberlain line', and 'McRae line' could predict the surgical intervention risk. Conclusion It was found that symptoms severity and McRae line value could be used as predictive markers in decision-making for surgical intervention. Additionally, it was concluded that a new scale called CHIASURG could predict surgical intervention risk validly and reliably.
dc.identifier.doi10.1080/01616412.2022.2089402
dc.identifier.endpage988
dc.identifier.issn0161-6412
dc.identifier.issn1743-1328
dc.identifier.issue11
dc.identifier.pmid35758154
dc.identifier.scopus2-s2.0-85132855365
dc.identifier.scopusqualityQ3
dc.identifier.startpage975
dc.identifier.urihttps://doi.org/10.1080/01616412.2022.2089402
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25283
dc.identifier.volume44
dc.identifier.wosWOS:000815821500001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Ltd
dc.relation.ispartofNeurological Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectChiari malformation; surgery; predictive marker; McRae line
dc.titlePossible predictive clinical and radiological markers in decision making for surgical intervention in patients with Chiari Malformation type 1
dc.typeArticle

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