Mill of non-neoplastic cranial complications of malignant disorders

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dc.contributor.authorYagmurlu, Banu
dc.contributor.authorAkyurek, Serap
dc.contributor.authorFitoz, Suat
dc.contributor.authorDemirkazik, Ahmet
dc.date.accessioned2020-06-25T17:44:33Z
dc.date.available2020-06-25T17:44:33Z
dc.date.issued2008
dc.departmentKırıkkale Üniversitesi
dc.descriptionFitoz, Suat/0000-0002-0180-0013
dc.description.abstractPURPOSE To depict the well-known and atypical magnetic resonance imaging (MRI) findings of non-neoplastic central nervous system (CNS) complications of extra-CNS tumors and portray additional information from advanced techniques, such as diffusion and perfusion MRI. MATERIALS AND METHODS MRI scans of 92 patients were retrospectively evaluated based on the non-neoplastic effects induced by treatment or the remote effects of the tumor itself. Patients with brain metastases and/or patients who had whole brain radiation therapy were excluded so as not to take the primary radiation effects into consideration. RESULTS Sixteen patients (9 females and 7 males; age range, 11-68 years; median age, 45 years) had positive findings other than brain metastases. Six patients had posterior reversible encephalopathies, 3 patients had chemotherapy toxicity to the white matter, and 2 patients had acute strokes involving the posterior fossa and bilateral anterior circulation territory. Three patients had bilateral radionecrosis of the temporal lobe due to radiotherapy given for the vicinal tumor (nasopharyngeal carcinoma). One patient had encephalitis in the bitemporal region and one patient had cerebellar degeneration, each of whom had a paraneoplastic syndrome. CONCLUSION One of the major and noteworthy complications of malignancies directly affecting survival is brain metastasis, but non-neoplastic complications are infrequently encountered and are thus underestimated, either due to the absence of a true diagnosis or the lack of information pertaining to the clinical outcome. It is important for the radiologist to recognize these effects so as to help the clinician develop an optimal treatment strategy and avoid irreversible complications.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.endpage68en_US
dc.identifier.issn1305-3612
dc.identifier.issue2en_US
dc.identifier.pmid18553277
dc.identifier.startpage61en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4141
dc.identifier.volume14en_US
dc.identifier.wosWOS:000256501400001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAvesen_US
dc.relation.ispartofDiagnostic And Interventional Radiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectchemotherapyen_US
dc.subjectradiotherapyen_US
dc.subjectbrainen_US
dc.subjectmagnetic resonance imagingen_US
dc.subjectmalignancyen_US
dc.titleMill of non-neoplastic cranial complications of malignant disordersen_US
dc.typeArticle

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