Beyond expectations: disease duration and psychological burden in psoriatic arthritis

Basit Öğe Kaydı
dc.authoridAlkan, Hakan/0000-0001-8461-9131
dc.authoridYurdakul, Ozan Volkan/0000-0003-4567-8133
dc.authoridTekeoğlu, İbrahim/0000-0003-3395-7178
dc.authoridKılıç, Gamze/0000-0003-1998-0988
dc.authoridOrhan, Kevser/0000-0001-8639-751X
dc.authoridNas, Kemal/0000-0002-5845-0851
dc.authoridBalta, Nihan Cüzdan/0000-0001-7238-657X
dc.contributor.authorKilic, Gamze
dc.contributor.authorKilic, Erkan
dc.contributor.authorTekeoglu, Ibrahim
dc.contributor.authorSargin, Betul
dc.contributor.authorCengiz, Gizem
dc.contributor.authorBalta, Nihan Cüzdan
dc.contributor.authorAlkan, Hakan
dc.date.accessioned2025-01-21T16:36:08Z
dc.date.available2025-01-21T16:36:08Z
dc.date.issued2023
dc.departmentKırıkkale Üniversitesi
dc.description.abstractThis study aims to investigate the relationship between disease duration and psychological burden in PsA and to identify the risk factors associated with psychological distress. Patients with PsA who met CASPAR classification criteria enrolled by Turkish League Against Rheumatism (TLAR)-Network. Patients were categorized into three groups based on disease duration: early stage (< 5 years), middle stage (& GE; 5, < 10 years), and late stage (& GE; 10 years). All patients underwent clinical and laboratory assessment using standardized protocol and case report forms. The associations between psychological variables and clinical parameters were assessed by a multivariate analysis. Of the 1113 patients with PsA (63.9% female), 564 (%50.7) had high risk for depression and 263 (%23.6) for anxiety. The risk of psychological burden was similar across all PsA groups, and patients with a higher risk of depression and anxiety also experienced greater disease activity, poorer quality of life, and physical disability. Multivariate logistic regression revealed that female gender (OR = 1.52), PsAQoL (OR = 1.13), HAQ (OR = 1.99), FiRST score (OR = 1.14), unemployment/retired (OR = 1.48) and PASI head score (OR = 1.41) were factors that influenced the risk of depression, whereas the current or past enthesitis (OR = 1.45), PsAQoL (OR = 1.19), and FiRST score (OR = 1.26) were factors that influenced the risk of anxiety. PsA patients can experience a comparable level of psychological burden throughout the course of their disease. Several socio-demographic and disease-related factors may contribute to mental disorders in PsA. In the present era of personalized treatment for PsA, evaluating psychiatric distress can guide tailored interventions that improve overall well-being and reduce disease burden.
dc.identifier.doi10.1007/s00296-023-05379-2
dc.identifier.issn0172-8172
dc.identifier.issn1437-160X
dc.identifier.pmid37418001
dc.identifier.scopus2-s2.0-85164103430
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1007/s00296-023-05379-2
dc.identifier.urihttps://hdl.handle.net/20.500.12587/24265
dc.identifier.wosWOS:001024953900001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer Heidelberg
dc.relation.ispartofRheumatology International
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectAnxiety; Arthritis; Psoriatic; Depression; Rheumatic diseases; Quality of life
dc.titleBeyond expectations: disease duration and psychological burden in psoriatic arthritis
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Tam Metin/Full Text
Boyut:
665.21 KB
Biçim:
Adobe Portable Document Format
İndir

Koleksiyon

WOS İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu