The association of androgenic sex steroids with serum lipid levels in postmenopausal women
Yükleniyor...
Tarih
2004
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wiley
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background. The aim of the present study was to examine the correlations between androgenic sex steroids and serum lipid levels in postmenopausal women. Methods. The study group included 72 postmenopausal women. Correlation analysis between serum hormone [dehydroepiandrosterone sulfate (DHEA-S), androstenedione, free testosterone and sex hormone binding globulin (SHBG)] and lipid {total cholesterol (TC), triglyceride (TG), high density lipoprotein-cholesterol (HDL-C), low density lipoprotein-cholesterol (LDL-C), lipoprotein(a) [Lp(a)], apolipoproteinA-1 (apoA-1) and apolipoprotein B (apo B)} levels was performed. Results. DHEA-S was found to be positively correlated with HDL-C (r = 0.231, p = 0.049) and negatively correlated with Lp(a) (r = -0.355, p = 0.002). These correlations were statistically significant even after adjustment for age and body mass index (BMI) (r = 0.332, p = 0.005 and r = -0.362, p = 0.002, respectively). SHBG was positively correlated with HDL-C (r = 0.352, p = 0.002). There was a significant but weaker correlation between SHBG and HDL-C levels after controlling for age and BMI (r = 0.243, p = 0.041). No other correlations were found between sex hormone and lipid levels. Conclusion. DHEA-S was found to be associated with a less atherogenic lipid profile in postmenopausal women.
Açıklama
Yucel, Aykan/0000-0002-5888-692X
Anahtar Kelimeler
dehydroepiandrosterone sulfate, high density lipoprotein-cholesterol, lipoprotein (a), postmenopause
Kaynak
Acta Obstetricia Et Gynecologica Scandinavica
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
83
Sayı
5
Künye
Noyan, V., Yucel, A., & Sagsoz, N. (2004). The association of androgenic sex steroids with serum lipid levels in postmenopausal women. Acta obstetricia et gynecologica Scandinavica, 83(5), 487–490.
