Influence of hematocrit and pump prime on cerebral oxygen saturation in on-pump coronary revascularization

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dc.contributor.authorMcCusker, Kevin
dc.contributor.authorChalafant, Anthony
dc.contributor.authorFoe, Gordon de
dc.contributor.authorGünaydın, Serdar
dc.contributor.authorVijay, Venkataramana
dc.date.accessioned2020-06-25T17:41:15Z
dc.date.available2020-06-25T17:41:15Z
dc.date.issued2006
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackground: The couplings between cerebral oxygenation (rSO(2)), on-pump hematocrit and circuit prime are explored in this study. Methods: Thirty-eight consecutive patients undergoing coronary revascularization with cardiopulmonary bypass (CPB) were matched on preoperative hematocrit < 40% and > 40% (n = 16). Similarly, six blood prime patients were matched with six crystalloid prime patients. Hematocrit and rSO(2) levels were then compared on CPB. Results: The preoperative hematocrit > 40% group retained higher levels on pump run (p < 0.01) and significantly higher rSO(2) prior to CPB (64.8 +/- 9.6 versus 73.2 +/- 7.3), and on and off CPB (61.1 +/- 8.8 versus 67.4 +/- 6.4). Blood priming increased absolute rSO(2) (2.3 +/- 6.3 versus -10.9 +/- 5.9) and % rSO(2) (4.7 +/- 11.8 versus -14.2 +/- 7.4%) in the low hematocrit group. Conclusion: Blood primes are instrumental in high-risk and low preoperative hematocrit patients in preventing cerebral oxygen desaturation during initiation and maintenance of CPB.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1191/0267659106pf863oa
dc.identifier.endpage155en_US
dc.identifier.issn0267-6591
dc.identifier.issn1477-111X
dc.identifier.issue3en_US
dc.identifier.pmid16817287
dc.identifier.scopus2-s2.0-33745313327
dc.identifier.scopusqualityQ1
dc.identifier.startpage149en_US
dc.identifier.urihttps://doi.org/10.1191/0267659106pf863oa
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3665
dc.identifier.volume21en_US
dc.identifier.wosWOS:000237223000004
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSage Publications Ltden_US
dc.relation.ispartofPerfusion-Uk
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleInfluence of hematocrit and pump prime on cerebral oxygen saturation in on-pump coronary revascularizationen_US
dc.typeArticle

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