Vitreous Humor Diffusion Changes in Behcet's Disease and Multiple Sclerosis

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dc.contributor.authorInal, Mikail
dc.contributor.authorSahan, Mehmet Hamdi
dc.contributor.authorErgun, Ufuk
dc.contributor.authorBilgili, Mirace Yasemin Karadeniz
dc.date.accessioned2020-06-25T18:29:53Z
dc.date.available2020-06-25T18:29:53Z
dc.date.issued2018
dc.departmentKırıkkale Üniversitesi
dc.descriptionINAL, MIKAIL/0000-0003-0642-7913
dc.description.abstractObjective: The aim of this study is to examine the diffusional changes in the vitreous humor in multiple sclerosis and Behcet's disease. Materials and Methods: Apparent diffusion coefficient values were investigated in diffusion magnetic resonance imaging scans of a total 111 vitreous, 31 of which were Behcet's disease patients, 40 had multiple sclerosis and 40 were healthy volunteers. Then, multiple sclerosis and Behcet's disease group were statistically compared with healthy volunteers and their apparent diffusion coefficient values amongst themselves. Results: There was no significant difference in terms of age and sex distribution among the three study groups (p>0.05). While there was no significant difference between multiple sclerosis and control groups (p>0.05), apparent diffusion coefficient values of Behcet's patients were significantly lower than multiple sclerosis and control groups (p<0.001). There was no significant difference between the patients with uveitis and those without uveitis in Behcet's disease. The apparent diffusion coefficient value of 2934,3(x10(-6) mm(2)/s) had a very high sensitivity and specificity (72.42-92.5%) for the Behcet's group, and by the use of ROC curve analysis, the detected cut off value for Behcet's disease was <= 2934,3(x10(-6) mm(2)/s). Conclusion: Our study showed that diffusion values in the vitreous humor were found to be decreased in patients with Behcet's disease, in comparison with the multiple sclerosis and the control groups. To the best of our knowledge, this has not been reported before.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.2174/1573405613666170619092555
dc.identifier.endpage937en_US
dc.identifier.issn1573-4056
dc.identifier.issn1875-6603
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-85056567971
dc.identifier.scopusqualityQ3
dc.identifier.startpage933en_US
dc.identifier.urihttps://doi.org/10.2174/1573405613666170619092555
dc.identifier.urihttps://hdl.handle.net/20.500.12587/7493
dc.identifier.volume14en_US
dc.identifier.wosWOS:000448798800010
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherBentham Science Publ Ltden_US
dc.relation.ispartofCurrent Medical Imaging Reviews
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectApparent diffusion coefficienten_US
dc.subjectdiffusion weighted MRIen_US
dc.subjectmultiple sclerosisen_US
dc.subjectBehcet's diseaseen_US
dc.subjectvitreous humoren_US
dc.subjectpatientsen_US
dc.titleVitreous Humor Diffusion Changes in Behcet's Disease and Multiple Sclerosisen_US
dc.typeArticle

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