Ankylosing spondylitis and multiple sclerosis in an HLA-B27 negative patient

Basit Öğe Kaydı
dc.contributor.authorTan, F.U.
dc.contributor.authorTellioglu, S.
dc.contributor.authorAydin, G.
dc.contributor.authorErdemoglu, A.K.
dc.contributor.authorKeles, I.
dc.date.accessioned2020-06-25T17:35:45Z
dc.date.available2020-06-25T17:35:45Z
dc.date.issued2004
dc.departmentKırıkkale Üniversitesi
dc.description.abstractA 41-year-old man presented with vertigo and gait disturbance. He gave a 10-year history of definite ankylosing spodylitis with low back pain, limitation of spinal mobility, decreased chest expansion and radiological evidence of bilateral sacroiliitis. The vertigo attacks started 3 years before and he had insidious evolution of bilateral leg weakness, increased muscle tension and walking disability during the past 2 years. The HLA haplotypes of the patient were A2, A33, B14, B49, Bw4, Bw6, Cw7 and he was HLA-B27 negative. The axial and sagittal cranial magnetic resonance imaging(MRI) showed multiple foci of increased signal intensity in the periventricular white matter and cerebellar hemispheres, suggesting a demyelinating disease process. The MRI of the spine showed centromedullar high intensity lesions at C7,Th7-8, Th 9-10 levels. The diagnosis was definite MS (primary progressive MS) as the patient had insidious neurological progression, CSF evidence of inthrathecal production of oligoclonal bands, conduction defects at VEP multiple brain and additional spinal cord lesions on MRI and continued progression for more than 1 year.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.endpage172en_US
dc.identifier.issn0300-9009
dc.identifier.issue4en_US
dc.identifier.pmid15742608
dc.identifier.scopus2-s2.0-14044275708
dc.identifier.scopusqualityQ2
dc.identifier.startpage169en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3198
dc.identifier.volume104en_US
dc.identifier.wosWOS:000227237800006
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherActa Medica Belgicaen_US
dc.relation.ispartofActa Neurologica Belgica
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectankylosing sponylitisen_US
dc.subjectmultiple sclerosisen_US
dc.subjectHLA B-27en_US
dc.titleAnkylosing spondylitis and multiple sclerosis in an HLA-B27 negative patienten_US
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
Ankylosing spondylitis and multiple sclerosis in an HLA-B27 negative patient.pdf
Boyut:
164.45 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin/Full Text
İndir

Koleksiyon

WOS İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu