The comparison and efficacy of 3 different alpha 1-adrenergic blockers for distal ureteral stones

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dc.contributor.authorYılmaz, Erdal
dc.contributor.authorBatislam, Ertan
dc.contributor.authorBasar, Mehmet Murad
dc.contributor.authorTuğlu, Devrim
dc.contributor.authorFerhat, Mehmet
dc.contributor.authorBasar, Halil
dc.date.accessioned2020-06-25T17:40:36Z
dc.date.available2020-06-25T17:40:36Z
dc.date.issued2005
dc.departmentKırıkkale Üniversitesi
dc.descriptionBatislam, Ertan/0000-0002-7493-4573;
dc.description.abstractPurpose: alpha 1-Adrenergic blockers have recently been shown to increase the rate of spontaneous passage of distal ureteral stones. We compared efficacy of 3 different alpha 1-adrenergic blockers for this purpose. Materials and Methods: A total of 114 patients between 18 and 65 years old who had lower ureteral stones were included in the study. Patients were randomly divided into 4 groups. Group 1 consisted of 28 patients and acted as the control group. Group 2 comprised 29 patients who received tamsulosin, group 3 was 28 patients receiving terazosin and group 4 was 29 patients receiving doxazosin. These agents were given for up to a month and hydration was also recommended simultaneously. Every week patients were controlled with x-rays of the kidneys, ureters, bladder and urinary ultrasonography. Meanwhile the number of pain episodes, analgesic dosage and the number of days for spontaneous passage of the calculi through the ureter were also recorded. Results: There were no differences between the groups with respect to age, weight, height, sex and stone size. The calculi passed through the ureter spontaneously in 15 patients in group 1 (53.57%), in 23 patients in group 2 (79.31%), in 22 patients in group 3 (78.57%), and in 22 patients in group 4 (75.86%). In groups 2 to 4 the number of pain episodes, expulsion time and analgesic dosage were found to be lower compared with those in group 1. Conclusions: alpha 1-Adrenergic blockers increase the frequency of spontaneous passage of the distal ureteral calculi. All 3 agents tested were equally efficacious.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1097/01.ju.0000158453.60029.0a
dc.identifier.endpage2012en_US
dc.identifier.issn0022-5347
dc.identifier.issn1527-3792
dc.identifier.issue6en_US
dc.identifier.pmid15879806
dc.identifier.scopus2-s2.0-18744402762
dc.identifier.scopusqualityQ1
dc.identifier.startpage2010en_US
dc.identifier.urihttps://doi.org/10.1097/01.ju.0000158453.60029.0a
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3500
dc.identifier.volume173en_US
dc.identifier.wosWOS:000229051700033
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Science Incen_US
dc.relation.ispartofJournal Of Urology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectadrenergic alpha-antagonistsen_US
dc.subjectureteral calculien_US
dc.titleThe comparison and efficacy of 3 different alpha 1-adrenergic blockers for distal ureteral stonesen_US
dc.typeArticle

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