Topical ophthalmic cyclosporine in the treatment of toxic epidermal necrolysis

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dc.contributor.authorOnaran, Zafer
dc.contributor.authorUsta, Gülşah
dc.contributor.authorKoçak, Mukadder
dc.contributor.authorÖrnek, Kemal
dc.contributor.authorBüyükkoçak, Ünase
dc.date.accessioned2020-06-25T15:14:46Z
dc.date.available2020-06-25T15:14:46Z
dc.date.issued2011
dc.departmentKırıkkale Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü
dc.description.abstractAim. To describe a case of toxic epidermal necrolysis (TEN) with ocular involvement treated with topical ophthalmic cyclosporine. Case Presentation. A 20-year-old woman developed TEN following administration of carbamazepine that was prescribed for epilepsy. Ophthalmic examination revealed bilateral pseudomembranous conjunctivitis. She was hospitalized in the intensive care unit and treated with intravenous corticosteroid and immunoglobulin. Topical cyclosporine was used in combination with topical corticosteroids for ocular surface disease. Following two months of ocular treatment, she recovered without any severe ocular complication. Ocular examination at the four-month followup showed a 2mm of symblepharon in the lower fornix as the sole pathologic finding. Conclusion. Topical ophthalmic cyclosporine may contribute to decrease the ophthalmic complications of TEN and should be considered in the acute stage of the disease. © 2011 Zafer Onaran et al.en_US
dc.identifier.doi10.1155/2011/416842
dc.identifier.issn16879627
dc.identifier.pmid22242029
dc.identifier.scopus2-s2.0-84875305429
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1155/2011/416842
dc.identifier.urihttps://hdl.handle.net/20.500.12587/2190
dc.identifier.volume2011en_US
dc.identifier.wosWOS:000215229900099
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherHindawi Limiteden_US
dc.relation.ispartofCase Reports in Medicine
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleTopical ophthalmic cyclosporine in the treatment of toxic epidermal necrolysisen_US
dc.typeArticle

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