A classification based on peak systolic velocity and end diastolic velocity predicts sildenafil citrate success

Basit Öğe Kaydı
dc.contributor.authorBaşar, M. Murad,
dc.contributor.authorAtan, A.
dc.contributor.authorTekdoğan, Ümit Y.
dc.contributor.authorBatislam, E.
dc.date.accessioned2020-06-25T17:35:16Z
dc.date.available2020-06-25T17:35:16Z
dc.date.issued2003
dc.departmentKırıkkale Üniversitesi
dc.descriptionBatislam, Ertan/0000-0002-7493-4573
dc.description.abstractObjective: To attempt to predict the success rate of sildenafil citrate in erectile dysfunction patients using penile Doppler ultrasonography (PDU) measurements of peak arterial velocity and end diastolic velocity. Material and Methods: A total of 212 patients (age range 27-76 years) with vascular pathologies were included in the study. Following a PDU test, the patients were divided into arterial insufficiency, veno-occlusive dysfunction and mixed vascular pathology groups. Subsequently, patients were given sildenafil citrate 50 mg and re-evaluated 1 month later to determine its efficacy. If it was ineffective, the dose was increased to 100 mg and patients were reassessed. Arterial insufficiency and veno-occlusive dysfunction patients were classified into mild, moderate and severe groups depending on peak systolic and end diastolic velocities. Results: The overall response rate in patients with arterial insufficiency was 74.5%, regardless of the degree of arterial insufficiency or the dose of sildenafil. The severe arterial insufficiency group had a much better response to 100 mg compared to 50 mg doses of sildenafil. Although the 50 mg sildenafil dose was effective in patients with minimal veno-occlusive dysfunction, 100 mg was better than 50 mg to achieve adequate erection in the mild and severe veno-occlusive dysfunction groups. Conclusions: Sildenafil was ineffective in patients with severe arterial and venous insufficiency. PDU and a simple classification of PDU velocity measurements can provide some important clues to the prognosis of treatment and avoid overtreatment and unnecessary office visits.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1080/00365590310014526
dc.identifier.endpage506en_US
dc.identifier.issn0036-5599
dc.identifier.issue6en_US
dc.identifier.pmid14675925
dc.identifier.scopus2-s2.0-0347126344
dc.identifier.scopusqualityN/A
dc.identifier.startpage502en_US
dc.identifier.urihttps://doi.org/10.1080/00365590310014526
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3076
dc.identifier.volume37en_US
dc.identifier.wosWOS:000187296700011
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherInforma Healthcareen_US
dc.relation.ispartofScandinavian Journal Of Urology And Nephrology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectarterial insufficiencyen_US
dc.subjecterectile dysfunctionen_US
dc.subjectpenile Doppler ultrasonographyen_US
dc.subjectsildenafilen_US
dc.subjectveno-occlusive diseaseen_US
dc.titleA classification based on peak systolic velocity and end diastolic velocity predicts sildenafil citrate successen_US
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
A classification based on peak systolic velocity and end diastolic velocity predicts sildenafil citrate success.pdf
Boyut:
249.41 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin/Full Text
İndir

Koleksiyon

WOS İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu