Evaluation and impact of chronic cough: comparison of specific vs generic quality-of-life questionnaires

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dc.contributor.authorKalpaklıoğlu, Ayşe Füsun
dc.contributor.authorKara, Türkan
dc.contributor.authorKurtipek, Ercan
dc.contributor.authorKoçyiğit, Pınar
dc.contributor.authorEkici, Aydanur
dc.contributor.authorEkici, Mehmet
dc.date.accessioned2020-06-25T17:40:38Z
dc.date.available2020-06-25T17:40:38Z
dc.date.issued2005
dc.departmentKırıkkale Üniversitesi
dc.descriptionEkici, Arif B/0000-0001-6099-7066
dc.description.abstractBackground: Chronic cough is a common condition that has a significant impact on health-related quality of life (HRQoL). Objective: To investigate whether chronic cough is associated with adverse psychological and physical effects on quality of life (QoL) using different HRQoL questionnaires. Methods: Forty patients were recruited for the study. The diagnostic workup was mainly based on the pathogenic triad in chronic cough: postnasal drip syndrome, asthma, and gastroesophageal reflux disease. The HRQoL was evaluated with the cough-specific quality-of-life questionnaire (CQLQ), Leicester Cough Questionnaire (LCQ), Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36), and Hospital Anxiety and Depression Scale. Results: Symptom scores were significantly correlated with the CQLQ and LCQ (beta =.415 and beta = -.272, respectively) but not with the SF-36. A statistically significant difference was found in all questionnaires, except the physical component summary domain of the SF-36, after specific therapy. Correlation between the 2 specific HRQoL questionnaires was moderate to high when pretreatment and posttreatment scores were compared (r = -0.42 and r = -0.60). Concurrent validity of the LCQ was higher than the CQLQ when compared with the SF-36 domains. The effect size of each specific QoL questionnaire was I or higher after treatment, whereas it was much less in the SF-36. There was no change in depression with treatment despite anxiety. Posttreatment symptom scores were related with anxiety (r > 0.40) Conclusions: Because HRQoL is important to patients, a cough-specific HRQoL instrument, either the CQLQ or LCQ, should be routinely used to optimally evaluate the impact of cough on patients and to evaluate the efficacy of cough-modifying agents. Ann Allergy Asthma Immunol. 2005;94:581-585.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1016/S1081-1206(10)61137-4
dc.identifier.endpage585en_US
dc.identifier.issn1081-1206
dc.identifier.issn1534-4436
dc.identifier.issue5en_US
dc.identifier.pmid15945562
dc.identifier.scopus2-s2.0-19044366481
dc.identifier.scopusqualityQ1
dc.identifier.startpage581en_US
dc.identifier.urihttps://doi.org/10.1016/S1081-1206(10)61137-4
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3506
dc.identifier.volume94en_US
dc.identifier.wosWOS:000229400900014
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Science Incen_US
dc.relation.ispartofAnnals Of Allergy Asthma & Immunology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleEvaluation and impact of chronic cough: comparison of specific vs generic quality-of-life questionnairesen_US
dc.typeArticle

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