The Nose as a Route for Therapy: Part 1. Pharmacotherapy

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dc.authoridToppila-Salmi, Sanna/0000-0003-0890-6686
dc.authoridPapadopoulos, Nikolaos/0000-0002-4448-3468
dc.authoridBAYAR MULUK, NURAY/0000-0003-3602-9289
dc.contributor.authorCingi, Cemal
dc.contributor.authorMuluk, Nuray Bayar
dc.contributor.authorMitsias, Dimitrios I.
dc.contributor.authorPapadopoulos, Nikolaos G.
dc.contributor.authorKlimek, Ludger
dc.contributor.authorLaulajainen-Hongisto, Anu
dc.contributor.authorHytonen, Maija
dc.date.accessioned2025-01-21T16:55:10Z
dc.date.available2025-01-21T16:55:10Z
dc.date.issued2021
dc.departmentKırıkkale Üniversitesi
dc.description.abstractThis article reviews nasal structure and function in the light of intranasal pharmacotherapy. The nose provides an accessible, fast route for local treatment of nose and sinus diseases, with lower doses than are necessary systemically and few adverse effects. It can also be used for other medications as it has sufficient surface area protected from local damage by mucociliary clearance, absence of digestive enzymes, responsive blood flow, and provides a rapid route to the central nervous system.
dc.identifier.doi10.3389/falgy.2021.638136
dc.identifier.issn2673-6101
dc.identifier.pmid35387039
dc.identifier.scopus2-s2.0-85129205471
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.3389/falgy.2021.638136
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25708
dc.identifier.volume2
dc.identifier.wosWOS:000994868100001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherFrontiers Media Sa
dc.relation.ispartofFrontiers In Allergy
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectintranasal route; nasal epithelium; mucociliary clearance; allergic rhinitis; chronic rhinosinusitis; lysine aspirin; saline douche; drug delivery
dc.titleThe Nose as a Route for Therapy: Part 1. Pharmacotherapy
dc.typeReview Article

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