Aquagenic palmar wrinkling induced by combined use of salazopyrin and indomethacin
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Tarih
2013
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Aquagenic palmar wrinkling (APW) is an uncommon dermatological condition, which manifests as asymptomatic or tender palmar papules and may cause discomfort and manual functional limitations during its flares. Despite some studies implying a relationship between cystic fibrosis (CF) and APW, there are also reports of APW cases without an accompanying CF. In this report we describe a 19-year-old ankylosing spondylitis patient, who developed APW lesions after the start of combined salazopyrin and indomethacin treatment. His palmar lesions were resistant to topical corticosteroid and aluminium hydroxide therapy and disappeared only after stopping the anti-inflammatory drugs. With this report, we aim to highlight and address this underrecognized dermatological condition and possible role of aquaporins in its pathogenesis. © 2013 S. Karger AG, Basel.
Açıklama
Anahtar Kelimeler
Aquagenic palmar wrinkling, Aquaporin, Cyclooxygenase, Indomethacin, Prostaglandins, Salazopyrin
Kaynak
Case Reports in Dermatology
WoS Q Değeri
N/A
Scopus Q Değeri
Q3
Cilt
5
Sayı
1
