P50 variations in Behcet's patients without neurologic findings
Yükleniyor...
Tarih
2007
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Riyadh Armed Forces Hospital
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: In the present study, subclinical lesion involvement was investigated using the P50 component in Behcet's patients without neurological manifestation. Methods: We performed this clinical research in Erciyes University, Faculty of Medicine between December 2000 and November 2001. The studies were carried out on 18 Behcet's patients without neurologic findings and 18 volunteers for control. Standard Ag/AgCl electrodes in plastic cups were used for monopolar EEG derivations. They were attached with electrode paste and tape at the Cz (vertex) according to the 10-20 system. The auditory stimuli were delivered in pairs. The P50 waves, which may be taken from approximately 50 msec from the stimuli, were collected by computer system. Amplitudes and latencies of the P50 components were measured in the same system. Results: This study showed that the suppression of P50 responses performed by the test stimuli, was significantly more decreased in Behcet's patients than the control subjects. Conclusion: The decrease of the suppression of the auditory P50 response to repeated stimuli reflects a deficit in the central nervous system's ability, such as attention, cognition, and sensory input in Behcet's patients and can be used as a neurophysiological marker in subclinical lesions in these patients.
Açıklama
Arslan, Mustafa/0000-0003-4882-5063; Suer, Cem/0000-0002-6455-6644
Anahtar Kelimeler
Kaynak
Neurosciences
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
12
Sayı
1
Künye
closedAccess
