P50 variations in Behcet's patients without neurologic findings

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dc.contributor.authorAscioglu, Meral
dc.contributor.authorArslan, Mustafa
dc.contributor.authorSüer, Cem
dc.contributor.authorAscioglu, Özcan
dc.contributor.authorÖzesmi, Ciğdem
dc.contributor.authorBorlu, Murat
dc.contributor.authorKöseoğlu, Emel
dc.date.accessioned2020-06-25T17:44:07Z
dc.date.available2020-06-25T17:44:07Z
dc.date.issued2007
dc.descriptionArslan, Mustafa/0000-0003-4882-5063; Suer, Cem/0000-0002-6455-6644
dc.description.abstractObjective: In the present study, subclinical lesion involvement was investigated using the P50 component in Behcet's patients without neurological manifestation. Methods: We performed this clinical research in Erciyes University, Faculty of Medicine between December 2000 and November 2001. The studies were carried out on 18 Behcet's patients without neurologic findings and 18 volunteers for control. Standard Ag/AgCl electrodes in plastic cups were used for monopolar EEG derivations. They were attached with electrode paste and tape at the Cz (vertex) according to the 10-20 system. The auditory stimuli were delivered in pairs. The P50 waves, which may be taken from approximately 50 msec from the stimuli, were collected by computer system. Amplitudes and latencies of the P50 components were measured in the same system. Results: This study showed that the suppression of P50 responses performed by the test stimuli, was significantly more decreased in Behcet's patients than the control subjects. Conclusion: The decrease of the suppression of the auditory P50 response to repeated stimuli reflects a deficit in the central nervous system's ability, such as attention, cognition, and sensory input in Behcet's patients and can be used as a neurophysiological marker in subclinical lesions in these patients.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.endpage52en_US
dc.identifier.issn1319-6138
dc.identifier.issue1en_US
dc.identifier.pmid21857619
dc.identifier.startpage50en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4017
dc.identifier.volume12en_US
dc.identifier.wosWOS:000244533700010
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherRiyadh Armed Forces Hospitalen_US
dc.relation.ispartofNeurosciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleP50 variations in Behcet's patients without neurologic findingsen_US
dc.typeArticle

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