Effects of Nd: YAG laser on tumour necrosis factor-alpha, interleukin-1beta and interferon-gamma levels in teeth with apical periodontitis: A clinical study

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dc.authoridTurkyilmaz, Ali/0000-0003-0641-0062
dc.contributor.authorBaris, Sevda Durust
dc.contributor.authorTurkyilmaz, Ali
dc.contributor.authorDerici, Mehmet Kursat
dc.date.accessioned2025-01-21T16:38:20Z
dc.date.available2025-01-21T16:38:20Z
dc.date.issued2023
dc.departmentKırıkkale Üniversitesi
dc.description.abstractThis study aimed to evaluate the levels of tumour necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1 beta) and interferon-gamma (IFN-gamma) with asymptomatic apical periodontitis (AP). A total of 60 participants were randomly divided into two groups: the conventional irrigation (control) and the Nd: YAG laser irradiation. The interstitial fluids were obtained after root canal cleaning (day 0) and 1 week later (day 7). The TNF-alpha a, IL-1 beta and IFN-gamma. levels were assayed using the enzyme-linked immunosorbent assay. The Mann-Whitney U, continuity correction chi-square, Pearson chi-square and Fisher exact tests were used. An increased level of cytokines on day 7 in the control group was observed, without statistically significant differences (p > 0.05). All cytokine levels decreased over time in the laser group. Only the IL-1 beta level showed a significant difference (p < 0.05). Nd: YAG irradiation has a positive effect on decreasing the proinflammatory cytokine level and may help to control infection in teeth with AP.
dc.description.sponsorshipKirikkale University Scientific Research Projects Coordination Department [2019/16]
dc.description.sponsorshipThis study, the thesis of Sevde Durust Baris,~was supported by the Kirikkale University Scientific Research Projects Coordination Department, with project number 2019/16.
dc.identifier.doi10.1111/aej.12799
dc.identifier.endpage664
dc.identifier.issn1329-1947
dc.identifier.issn1747-4477
dc.identifier.issue3
dc.identifier.pmid37746745
dc.identifier.scopus2-s2.0-85172325667
dc.identifier.scopusqualityQ2
dc.identifier.startpage657
dc.identifier.urihttps://doi.org/10.1111/aej.12799
dc.identifier.urihttps://hdl.handle.net/20.500.12587/24640
dc.identifier.volume49
dc.identifier.wosWOS:001070849600001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofAustralian Endodontic Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectasymptomatic apical periodontitis; cytokines; inflammatory mediators; Nd: YAG laser
dc.titleEffects of Nd: YAG laser on tumour necrosis factor-alpha, interleukin-1beta and interferon-gamma levels in teeth with apical periodontitis: A clinical study
dc.typeArticle

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