Mean Platelet Volume Decreases in Adult Patients With Obstructive Sleep Apnea After Uvulopalatal Flap Surgery

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dc.contributor.authorSimsek, Gokce
dc.contributor.authorHaytoglu, Suheyl
dc.contributor.authorMuluk, Nuray Bayar
dc.contributor.authorArikan, Osman Kursat
dc.contributor.authorCortuk, Mustafa
dc.contributor.authorKiraz, Kemal
dc.date.accessioned2020-06-25T18:12:46Z
dc.date.available2020-06-25T18:12:46Z
dc.date.issued2015
dc.departmentKırıkkale Üniversitesi
dc.descriptionSIMSEK, GOKCE/0000-0001-5281-0986
dc.description.abstractAim:The main purpose of the study was to investigate changes in mean platelet volume (MPV) values in patients with obstructive sleep apnea syndrome (OSAS) who had undergone uvulopalatal flap (UPF) surgery.Method:The study included a review of the medical records of 37 adult patients who had undergone UPF surgery after being diagnosed with OSAS. The baseline blood parameters of patients, including the MPV and platelet distribution width (PDW) values, were measured and repeated 3 months after treatment. Polysomnographic evaluations of the patients were also performed during admission and the 3rd month control. Comparisons of MPV values and their correlation with polysomnographic parameters were the main outcomes measured.Results:The blood parameters of all patients were similar except for MPV values, which were significantly lower after treatment (P<0.001). Patients' apnea hypopnea index (AHI) and apnea episodes were significantly reduced after the UPF surgery, whereas their oxygen saturation significantly increased (P<0.001). The MPV values were not correlated with polysomnographic parameters (P>0.05).Conclusion:The UPF surgery, which is a relatively simple surgical intervention to treat OSAS, alleviates nocturnal hypoxic episodes and lowers platelet volume. These may both be important predictors of adverse cardiovascular outcomes related to OSAS.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1097/SCS.0000000000001954
dc.identifier.endpage2154en_US
dc.identifier.issn1049-2275
dc.identifier.issn1536-3732
dc.identifier.issue7en_US
dc.identifier.pmid26468800
dc.identifier.scopus2-s2.0-84945196050
dc.identifier.scopusqualityQ3
dc.identifier.startpage2152en_US
dc.identifier.urihttps://doi.org/10.1097/SCS.0000000000001954
dc.identifier.urihttps://hdl.handle.net/20.500.12587/6034
dc.identifier.volume26en_US
dc.identifier.wosWOS:000367905900025
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofJournal Of Craniofacial Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectApnea-hypopnea indexen_US
dc.subjectmean platelet volumeen_US
dc.subjectOSASen_US
dc.subjectuvulopalatal flap surgeryen_US
dc.titleMean Platelet Volume Decreases in Adult Patients With Obstructive Sleep Apnea After Uvulopalatal Flap Surgeryen_US
dc.typeArticle

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