Malondialdehyde and nitric oxide levels and catalase, superoxide dismutase, and glutathione peroxidase levels in maternal blood during different trimesters of pregnancy and in the cord blood of newborns

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dc.contributor.authorYuksel, Sevda
dc.contributor.authorYigit, Ayse Arzu
dc.date.accessioned2020-06-25T18:15:52Z
dc.date.available2020-06-25T18:15:52Z
dc.date.issued2015
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackground/aim: To determine whether levels of malondialdehyde (MDA), nitric oxide (NO), superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT) change during the 3 trimesters of pregnancy, and to compare the third trimester of pregnancy with newborn cord blood in respect to the levels of MDA, NO, and antioxidant enzymes. Materials and methods: Maternal blood samples were collected at 9-13, 22-26, and 36-40 weeks of gestation. Cord blood was collected at the time of delivery. Results: NO levels and GPx activity were higher in the second and third trimesters than in the first trimester. MDA level was lower in the third trimester and SOD and CAT activities were lower in the second and third trimesters than the first trimester. In cord blood, MDA and NO levels were lower while CAT and GPx activities were higher than in the third trimester of pregnancy. Conclusion: These results suggest that the balance of free radical and antioxidant production during pregnancy ensures healthy fetus growth and development.en_US
dc.description.sponsorshipKirikkale University Research FundKirikkale University [2010/1]en_US
dc.description.sponsorshipThis study was summarized from a PhD thesis with the same title written by Sevda Yuksel. The work in this study was supported by the Kirikkale University Research Fund, Project No. 2010/1.en_US
dc.identifier.citationYüksel, Sevda And Yiğit, Ayşe Arzu (2015) "Malondialdehyde and nitric oxide levels and catalase, superoxide dismutase, and glutathione peroxidase levels in maternal blood during different trimesters ofpregnancy and in the cord blood of newborns," Turkish Journal of Medical Sciences: 45(2), 454-459.en_US
dc.identifier.doi10.3906/sag-1311-72
dc.identifier.endpage459en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue2en_US
dc.identifier.pmid26084141
dc.identifier.scopus2-s2.0-84926362363
dc.identifier.scopusqualityQ1
dc.identifier.startpage454en_US
dc.identifier.urihttps://doi.org/10.3906/sag-1311-72
dc.identifier.urihttps://hdl.handle.net/20.500.12587/6322
dc.identifier.volume45en_US
dc.identifier.wosWOS:000352482000030
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTubitak Scientific & Technical Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal Of Medical Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMaternal blooden_US
dc.subjectcatalaseen_US
dc.subjectcord blooden_US
dc.subjectglutathione peroxidaseen_US
dc.subjectmalondialdehydeen_US
dc.subjectnitric oxideen_US
dc.subjectsuperoxide dismutaseen_US
dc.titleMalondialdehyde and nitric oxide levels and catalase, superoxide dismutase, and glutathione peroxidase levels in maternal blood during different trimesters of pregnancy and in the cord blood of newbornsen_US
dc.typeArticle

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