Investigation of The Effectiveness of Plant Based Algan Hemostatic Agent in a Rat Model of Femoral Arterial Bleeding

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dc.authoridDizdaroglu, Hazal/0000-0003-4909-3212
dc.authoridEkici, Hüsamettin/0000-0001-6403-737X
dc.authoridYeşilada, Erdem/0000-0002-1348-6033
dc.authoridKumandaş, Ali/0000-0002-7679-2126
dc.authoridÖzbaykuş, Abdullah Canberk/0000-0001-8038-0629
dc.authoridMidi, Ahmet/0000-0002-6197-7654
dc.contributor.authorEkici, Hüsamettin
dc.contributor.authorKumandaş, Ali
dc.contributor.authorÖzbaykuş, Abdullah Canberk
dc.contributor.authorDizdaroglu, Hazal
dc.contributor.authorMidi, Ahmet
dc.contributor.authorBalik, Mehmet Sabri
dc.contributor.authorYesilada, Erdem
dc.date.accessioned2025-01-21T16:33:36Z
dc.date.available2025-01-21T16:33:36Z
dc.date.issued2022
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjective: The aim of this study is to evaluate the efficacy of the Algan Hemostatic Agent (AHA) available in three different physical form (liquid, powder and sponge absorbed) in the femoral artery incision model in rats. Methods: A total of sixty-four 5-7 weeks old rats were used in the study. Rats were randomly divided into 8 groups each consisting of eight rats (4 groups heparinized and 4 groups non-heparinized). An experimental femoral artery incision was created. As a control, physiological saline absorbed sponge was applied. AHA liquid, AHA powder and AHA sponge absorbed forms were applied to the experimental groups. Results: Upon application to the bleeding sites, all the AHA forms stopped bleeding in a significantly shorter time compared to the control group (p<0.05). In contrast, bleeding in control group could not be controlled within 4 minutes. The best result was in AHA powder form and it was able to control bleeding in the non-heparinized group at 87.5% in the first minute and 12.5% in the second minute. In the heparinize group, the AHA powder form was able to control the bleeding at 62.5% in the first minute and 37.5% in the second minute. Conclusion: This study shows that AHA is a highly effective and promising hemostatic agent in bleeding control.
dc.description.sponsorshipAlgan Group Health Services (Algan Group Health Services Import and Export Industry and Trade Limited Company, Istanbul, Turkey)
dc.description.sponsorshipThis study supported by The Algan Group Health Services (Algan Group Health Services Import and Export Industry and Trade Limited Company, Istanbul, Turkey). However, the company had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
dc.identifier.doi10.14235/bas.galenos.2021.5544
dc.identifier.endpage95
dc.identifier.issn2148-2373
dc.identifier.issue1
dc.identifier.startpage88
dc.identifier.trdizinid1170977
dc.identifier.urihttps://doi.org/10.14235/bas.galenos.2021.5544
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay1170977
dc.identifier.urihttps://hdl.handle.net/20.500.12587/23812
dc.identifier.volume10
dc.identifier.wosWOS:000748399400015
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherBezmialem Vakif Univ
dc.relation.ispartofBezmialem Science
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectAlgan; hemostasis; femoral artery; rat
dc.titleInvestigation of The Effectiveness of Plant Based Algan Hemostatic Agent in a Rat Model of Femoral Arterial Bleeding
dc.typeArticle

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