Antibacterial activity of venom from funnel web spider Agelena labyrinthica (Araneae: Agelenidae)

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dc.contributor.authorBenli, M.
dc.contributor.authorYigit, N.
dc.date.accessioned2020-06-25T17:48:04Z
dc.date.available2020-06-25T17:48:04Z
dc.date.issued2008
dc.description.abstractSince the number of microorganisms that are resistant to antibiotics has been increasing steadily, the need for combating these pathogens requires new pharmaceutical agents. To produce these substances, new models have been developed in recent decades. In our study, the venom of Agelena labyrinthica (Clerck, 1757) (Araneae: Agelenidae) was tested against ten bacterial strains, specifically, testing 1/100, 1/10 and 1/1 fractions of diluted venom against these bacteria. While the 1/100 dilution was successful in only one of ten bacterial strains, the 1/10 and the 1/1 were effective on six of ten bacterial strains. The most effective results, among these three different concentrations, were observed on Bacillus subtilis. The other five strains that were also sensitive to the dilutions showed similar inhibition zones. Morphological alterations on bacterial cells and comparison with normal cells were accomplished by scanning electron microscopy (SEM). The venom-treated cells, due to their loss of cytoplasm, shrank and presented cell wall depression.en_US
dc.description.sponsorshipTechnical and Research Council of TurkeyTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [TBAG-2286, 103T040]en_US
dc.description.sponsorshipThis study was supported by a grant from the Technical and Research Council of Turkey (TUBITAK, TBAG-2286 [103T040]).en_US
dc.identifier.citationBenli, Mehlika & Yigit Kayhan, Nazife. (2008). Antibacterial activity of venom from funnel web spider Agelena labyrinthica (Araneae: Agelenidae). Journal of Venomous Animals and Toxins Including Tropical Diseases - J VENOM ANIM TOXINS TROP DIS. 14(4), 641-650.en_US
dc.identifier.doi10.1590/S1678-91992008000400007
dc.identifier.endpage650en_US
dc.identifier.issn1678-9199
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-58049186780
dc.identifier.scopusqualityQ1
dc.identifier.startpage641en_US
dc.identifier.urihttps://doi.org10.1590/S1678-91992008000400007
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4282
dc.identifier.volume14en_US
dc.identifier.wosWOS:000267352500007
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherBmcen_US
dc.relation.ispartofJournal Of Venomous Animals And Toxins Including Tropical Diseases
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAgelena labyrinthicaen_US
dc.subjectvenomen_US
dc.subjectantimicrobial activityen_US
dc.titleAntibacterial activity of venom from funnel web spider Agelena labyrinthica (Araneae: Agelenidae)en_US
dc.typeArticle

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