Ongoing pregnancies from early retrieval of prematurely developing antral follicles after DHEA supplementation

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dc.contributor.authorSoenmezer, Murat
dc.contributor.authorCil, Aylin Pelin
dc.contributor.authorOktay, Kutluk
dc.date.accessioned2020-06-25T17:48:09Z
dc.date.available2020-06-25T17:48:09Z
dc.date.issued2009
dc.departmentKırıkkale Üniversitesi
dc.description.abstractTwo patients with severely diminished ovarian reserve who were refractory to aggressive ovarian stimulation conceived with oocytes from prematurely developing antral follicles after dehydroepiandrosterone supplementation. The first patient had 11 and 14.5 mm, and the second patient had 13 mm antral follicles on cycle days 2 and 3 respectively. In the first case, no ovarian Stimulation was performed, while the second case received one dose of gonadotrophins with a gonadotrophin-releasing hormone antagonist. Following very early human chorionic gonadotrophin (HCG) triggering on cycle day 5, when antral follicles reached 15 and 18.5 mm in the first case, and 19 mm in the second case, IVF intracytoplasmic sperm injection treatment resulted in pregnancies in both cases, which are currently ongoing at 35 and 14 weeks of gestation. The results in these patients show that pregnancy can be achieved in poor responder patients with prematurely developing antral follicles following early HCG triggering based on follicle size rather than cycle day, with no or minimal stimulation. Whether DHEA Supplementation had any impact on the success of these cycles remains to be determined.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.endpage819en_US
dc.identifier.issn1472-6483
dc.identifier.issn1472-6491
dc.identifier.issue6en_US
dc.identifier.pmid20031022
dc.identifier.scopus2-s2.0-77449125682
dc.identifier.scopusqualityQ1
dc.identifier.startpage816en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4333
dc.identifier.volume19en_US
dc.identifier.wosWOS:000273671000009
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Sci Ltden_US
dc.relation.ispartofReproductive Biomedicine Online
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectantral follicleen_US
dc.subjectDHEAen_US
dc.subjectpoor ovarian reserveen_US
dc.titleOngoing pregnancies from early retrieval of prematurely developing antral follicles after DHEA supplementationen_US
dc.typeArticle

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