Crystal structure of 3,3-dichloro-N-p-methoxyphenyl-4-(2-phenyistryl)-2-azetidinone
Yükleniyor...
Tarih
2003
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Japan Soc Analytical Chemistry
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
3.3-Dichloro-N-p-methoxyphenyl-4-(2-phenylstryl)-2-azetidinone (C22H15Cl2NO2) was studied by X-Ray analysis, which indicated a monoclinic space group, P2(1)/c, with a = 9.619(5), b = 13.879(4), c = 14.161(5)Angstrom, beta = 100. 16(3)degrees, V = 1860.8(13)Angstrom(3), Z = 4, D-c = 1.414 g cm(-3), mu(Mo K-a) = 0.366 mm(-1) and F-000 = 816. The structure was solved by direct methods and refined to R = 0.041 for 4026 reflections [I > 2sigma(I). The beta-lactam ring (2-azetidinone) has antimicrobial affects. The substituents of the methoxyphenyl and phenyl substituents do not change the activity property of the betalactam ring, and the activity properties depend on the planarity of the beta-lactam ring.
Açıklama
kabak, mehmet/0000-0001-6097-9394
Anahtar Kelimeler
Kaynak
Analytical Sciences
WoS Q Değeri
Q3
Scopus Q Değeri
Q3
Cilt
19
Sayı
6
Künye
closedAccess
