Allergic Rhinitis: Can We Identify Nonadherence to Therapy and Its Predictors Easily in Daily Practice?

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dc.contributor.authorKalkan, I. Koca
dc.contributor.authorKavut, A. Baccioglu
dc.contributor.authorKalpaklioglu, A. F.
dc.date.accessioned2020-06-25T18:07:39Z
dc.date.available2020-06-25T18:07:39Z
dc.date.issued2013
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackground: Allergic rhinitis (AR) is a common chronic condition with significant consequences if left untreated (eg, poor health outcomes, disease progression, and increased health care costs). However, about half of all patients do not fill their prescription. The factors associated with adherence are complex, and many remain poorly defined and understood. Objectives: This pilot study had 2 objectives. First, to determine whether the medication adherence report scale (MARS) can be applied to identify adherence/nonadherence in patients with AR using patients with chronic obstructive pulmonary disease (COPD) as controls. Second, to identify AR profiles that indicate a particularly high risk of nonadherence. Methods: AR patients completed the Eysenck Personality Questionnaire-Revised Abbreviated-Form (EPQR-A), the Short Form 36 Health Survey (SF-36), the Mini Rhinitis Quality of Life Questionnaire (Mini-RQLQ), and the MARS. Symptom severity was assessed before and after treatment. Results: The study population comprised 85 AR patients and 50 COPD patients. Females had worse adherence (significant only in total and unintentional scores) and higher extraversion scores. None of the personality traits predicted adherence. Neuroticism was negatively correlated with the SF-36 score (P<.001). A low to moderate correlation was observed between posttreatment improvement in specific/generic health-related quality of life and MARS scores in AR patients (P=.002, r=0.332; and P=.022, r=-0.251; respectively). Higher educational level was found to significantly increase adherence (P=.01, r=0.223). Conclusions: Our study did not reveal a personality effect. However, it did suggest that use of a brief, self-completed medication adherence questionnaire in daily practice can enable health professionals to identify suboptimal adherence in patients who would benefit from close follow-up.en_US
dc.identifier.citationKoca Kalkan, I., Baccioglu Kavut, A., & Kalpaklioglu, A. F. (2013). Allergic rhinitis: can we identify nonadherence to therapy and its predictors easily in daily practice?. Journal of investigational allergology & clinical immunology, 23(5), 315–322.en_US
dc.identifier.endpage322en_US
dc.identifier.issn1018-9068
dc.identifier.issn1698-0808
dc.identifier.issue5en_US
dc.identifier.pmid24260976
dc.identifier.scopus2-s2.0-84881155409
dc.identifier.scopusqualityQ2
dc.identifier.startpage315en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12587/5632
dc.identifier.volume23en_US
dc.identifier.wosWOS:000323873700004
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherEsmon Publicidad S A, Dept Allergy & Clin Immunol, Clin Univ Navarraen_US
dc.relation.ispartofJournal Of Investigational Allergology And Clinical Immunology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAllergic rhinitisen_US
dc.subjectMedication adherenceen_US
dc.subjectPersonality traiten_US
dc.subjectHealth-related quality of lifeen_US
dc.titleAllergic Rhinitis: Can We Identify Nonadherence to Therapy and Its Predictors Easily in Daily Practice?en_US
dc.typeArticle

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