Choroidal thickness changes in non-treated acute and ranibizumab-treated chronic central serous chorioretinopathy

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dc.contributor.authorYumusak, Erhan
dc.contributor.authorGokcinar, Nesrin Buyuktortop
dc.contributor.authorOrnek, Kemal
dc.date.accessioned2020-06-25T18:29:23Z
dc.date.available2020-06-25T18:29:23Z
dc.date.issued2018
dc.departmentKırıkkale Üniversitesi
dc.descriptionGokcinar, Nesrin Buyuktortop/0000-0001-7795-5188
dc.description.abstractTo evaluate the changes in subfoveal retinal, and choroidal thicknesses (CT) in the non-treated acute and the ranibizumab-treated chronic central serous chorioretinopathy (CSCR) patients. This retrospective study included 32 eyes of 32 consecutive patients with CSCR. There were 12 patients who presented with a spontaneous resolution of CSCR (Group 1) and 20 patients who were treated with ranibizumab for persistent subretinal fluid (SRF) (Group 2). Optical coherence tomography (OCT) imaging of subfoveal retinal thickness and enhanced depth imaging OCT of CT at subfoveal; at nasal and temporal 500 mu m (T500); at nasal and temporal 1500 mu m (T1500) were analyzed. The Student t test and multivariate analysis were used to compare variables within and between groups, respectively and correlations were analyzed using Pearson correlation coefficient. A P value of P<.05 was accepted as significant. The mean patient age was 38.94 +/- 8.41 years (range, 20-53 years). Female/male ratio was 4/28. The mean duration of follow-up was 21.6 +/- 8.2 months in the chronic CSCR group. Visual acuity improved and central foveal thickness (FT) decreased significantly in both groups. CT decreased significantly only at nasal 1500mm (N1500) in the acute group and at all measured points in the chronic group compared with baseline, except at T500 (P =. 07). No significant difference in central FT was detected between the 2 groups. Compared with the acute group, baseline subfoveal CT was significantly higher in chronic patients. There was a significant difference between the groups in baseline and final CT at T500. No significant difference was found at T1500. At nasal 500mm and N1500, the difference between the groups was significant only for final CT values. Chronic CSCR was associated with higher baseline CT values in the subfoveal region and at T500. CT significantly decreased at most of the measured points in ranibizumab-treated chronic CSCR patients, whereas it significantly decreased only at 1 point in spontaneously resolved acute CSCR patients.en_US
dc.identifier.citationYumusak, E., Gokcinar, N. B., & Ornek, K. (2018). Choroidal thickness changes in non-treated acute and ranibizumab-treated chronic central serous chorioretinopathy. Medicine, 97(43), e12885.en_US
dc.identifier.doi10.1097/MD.0000000000012885
dc.identifier.issn0025-7974
dc.identifier.issn1536-5964
dc.identifier.issue43en_US
dc.identifier.pmid30412084
dc.identifier.scopus2-s2.0-85056403942
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1097/MD.0000000000012885
dc.identifier.urihttps://hdl.handle.net/20.500.12587/7283
dc.identifier.volume97en_US
dc.identifier.wosWOS:000452441600027
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofMedicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectcentral serous chorioretinopathyen_US
dc.subjectchoroidal thicknessen_US
dc.subjectoptical coherence tomographyen_US
dc.subjectranibizumaben_US
dc.subjectretinal thicknessen_US
dc.titleChoroidal thickness changes in non-treated acute and ranibizumab-treated chronic central serous chorioretinopathyen_US
dc.typeArticle

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