Breast cancer diagnosis following ovarian stimulation: Are the tumours different?

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dc.contributor.authorSönmezer, Murat
dc.contributor.authorÇil, Aylin Pelin
dc.contributor.authorÖktem, Özgür
dc.contributor.authorOktay, Kutluk
dc.date.accessioned2020-06-25T17:49:23Z
dc.date.available2020-06-25T17:49:23Z
dc.date.issued2010
dc.departmentKırıkkale Üniversitesi
dc.description.abstractDemographic data and tumour characteristics of 18 patients (study group) diagnosed with breast cancer within 24 months of undergoing ovarian stimulation with either gonadotrophins or clomiphene citrate were evaluated and compared with similar 102 age-matched women diagnosed with breast cancer without prior infertility treatment (control group). Eight out of 17 (47.1%) patients in the study group and 35/95 (36.8%) patients in the control group had positive family history for breast cancer. Median tumour size was similar in the study and control groups (both 1.3 cm). Both groups were comparable regarding tumour histological types and oestrogen receptor, progesterone receptor and Her2/Neu expression status. Albeit not significant, stage 0 tumours were more prevalent in the study group compared with the control group (22.2% versus 10.5%), and there were no stage III tumours in the study group as opposed to 7/95 in the control group. In conclusion, breast cancer diagnosed within the first 2 years following infertility treatment is similar in tumour characteristics compared with those occurring in patients without prior infertility treatment. (C) 2010, Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1016/j.rbmo.2010.05.006
dc.identifier.endpage271en_US
dc.identifier.issn1472-6483
dc.identifier.issue2en_US
dc.identifier.pmid20615755
dc.identifier.scopus2-s2.0-78650225823
dc.identifier.scopusqualityQ1
dc.identifier.startpage266en_US
dc.identifier.urihttps://doi.org/10.1016/j.rbmo.2010.05.006
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4704
dc.identifier.volume21en_US
dc.identifier.wosWOS:000281172300016
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherReproductive Healthcare Ltden_US
dc.relation.ispartofReproductive Biomedicine Online
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectbreast canceren_US
dc.subjectfamily historyen_US
dc.subjectHer2/Neuen_US
dc.subjectoestrogen receptoren_US
dc.subjectovulation inductionen_US
dc.subjectprogesterone receptoren_US
dc.titleBreast cancer diagnosis following ovarian stimulation: Are the tumours different?en_US
dc.typeArticle

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