Activation of 6-bromoquinoline by nitration: synthesis of morpholinyl and piperazinyl quinolines

Basit Öğe Kaydı
dc.contributor.authorÇakmak, Osman
dc.contributor.authorÖkten, Salih
dc.contributor.authorAlimli, Dilek
dc.contributor.authorSaddiqa, Aisha
dc.contributor.authorErsanlı, Cem Cüneyt
dc.date.accessioned2020-06-25T18:29:59Z
dc.date.available2020-06-25T18:29:59Z
dc.date.issued2018
dc.departmentKırıkkale Üniversitesi
dc.descriptionAlimli, Dilek/0000-0003-4564-9447; Hokelek, Tuncer/0000-0002-8602-4382; Okten, Salih/0000-0001-9656-1803
dc.description.abstractQuinoline forms the key skeletal component of a number of important natural products and pharmacologically-active compounds. Despite a tremendous amount of research pertaining to the derivatization of quinoline, very few general synthetic routes are described in the literature starting from quinoline or tetrahydroquinoline. A simple and convenient method for the polyfunctionalization of quinolines via nitration of bromoquinolines has been developed. This method represents a new synthetic approach to convert brominated nitroquinoline derivatives into useful cyclic amines via nucleophilic-substitution (SNAr) reaction. [GRAPHICS] .en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [112T394]en_US
dc.description.sponsorshipThis study was financially supported by grants from the Scientific and Technological Research Council of Turkey (TUBITAK, Project number: 112T394). The authors thank the Scientific and Technological Research Application and Research Center, Sinop University, Turkey, for the use of the Bruker D8-QUEST diffractometer.en_US
dc.identifier.citationÇakmak, O., Okten, S., Alimli, D., Saddiqa, A., & Ersanli, C. C., (2018). Activation of 6-bromoquinoline by nitration: synthesis of morpholinyl and piperazinyl quinolines. ARKIVOC , vol.2018, 362-374.en_US
dc.identifier.doi10.24820/ark.5550190.p010.374
dc.identifier.endpage374en_US
dc.identifier.issn1551-7004
dc.identifier.issn1551-7012
dc.identifier.scopus2-s2.0-85049176940
dc.identifier.scopusqualityQ4
dc.identifier.startpage362en_US
dc.identifier.urihttps://doi.org/10.24820/ark.5550190.p010.374
dc.identifier.urihttps://hdl.handle.net/20.500.12587/7523
dc.identifier.wosWOS:000438799100030
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherArkat Usa Incen_US
dc.relation.ispartofArkivoc
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectNitrationen_US
dc.subjectN-oxidationen_US
dc.subject6-bromoquinolineen_US
dc.subjectaminoquinolineen_US
dc.subjectquinoline N-oxidesen_US
dc.subjectmorpholinyl and piperazinyl quinolinesen_US
dc.titleActivation of 6-bromoquinoline by nitration: synthesis of morpholinyl and piperazinyl quinolinesen_US
dc.typeArticle

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