Hydroxyapatite-based nanoparticles as a coating material for the dentine surface: An antibacterial and toxicological effect

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dc.contributor.authorErdem, Umit
dc.contributor.authorDogan, Mustafa
dc.contributor.authorMetin, Aysegul U.
dc.contributor.authorBaglar, Serdar
dc.contributor.authorTurkoz, Mustafa B.
dc.contributor.authorTurk, Mustafa
dc.contributor.authorNezir, Saffet
dc.date.accessioned2021-01-14T18:11:10Z
dc.date.available2021-01-14T18:11:10Z
dc.date.issued2020
dc.departmentKKÜ
dc.descriptionTurkoz, Mustafa Burak/0000-0002-4127-7650; Dogan, Mustafa/0000-0002-4437-566X
dc.description.abstractIn this study, nano sized hydroxyapatite (nHAp) and Ag(I) doped hydroxyapatite (Ag-nHAp) particles were synthesized by the precipitation method and used as a coating material for remineralization on caries-affected dentine samples. Characterization studies of both the synthesized hydroxyapatite-based particles and the coated dentine samples were performed using instrumental techniques such as SEM and FFIR, and then toxicity and antibacterial properties were also evaluated. It was observed that dentine samples were effectively coated by both nHAp and Ag center dot nHAp particles which have no toxic effects. Furthermore, the costing of nano-hydroxyapatite on dentine samples positively contributed to the viability of L929 fibroblast cells and also provided an antibacterial effect against to bacteria such as S. mutants, C. albicans and E. coli bacteria that are most frequently caused caries in the teeth. While all type of bacteria was eliminated by the nHAp coated dentine samples at 24th, Ag-nHAp coated dentine samples removed to all bacteria type at 1st.en_US
dc.description.sponsorshipKirikkale University Research FundKirikkale University [2019/038]en_US
dc.description.sponsorshipThe authors would like to express their gratitude to Kirikkale University Research Fund for its financial support. Project Number: 2019/038.en_US
dc.identifier.citationBu makale açık erişimli değildir.en_US
dc.identifier.doi10.1016/j.ceramint.2019.08.260
dc.identifier.endpage280en_US
dc.identifier.issn0272-8842
dc.identifier.issn1873-3956
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85071694765
dc.identifier.scopusqualityQ1
dc.identifier.startpage270en_US
dc.identifier.urihttps://doi.org/10.1016/j.ceramint.2019.08.260
dc.identifier.urihttps://hdl.handle.net/20.500.12587/12903
dc.identifier.volume46en_US
dc.identifier.wosWOS:000498748300032
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherELSEVIER SCI LTDen_US
dc.relation.ispartofCERAMICS INTERNATIONAL
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDentine coatingen_US
dc.subjectNanoparticlesen_US
dc.subjectHydroxyapatiteen_US
dc.subjectSilveren_US
dc.subjectAntibacterialen_US
dc.subjectCytotoxicityen_US
dc.titleHydroxyapatite-based nanoparticles as a coating material for the dentine surface: An antibacterial and toxicological effecten_US
dc.typeArticle

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