Prolonged P Wave Peak Time May Be a Sign of LV Diastolic Dysfunction in the Coronary Slow Flow Phenomenon

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dc.authoridINCI, UMIT/0000-0002-7412-1222
dc.authoridAkyuz, Abdurrahman/0000-0003-2491-6593
dc.authoridIsik, Ferhat/0000-0002-1438-3327
dc.contributor.authorAslan, Burhan
dc.contributor.authorIsik, Ferhat
dc.contributor.authorAkyuz, Abdurrahman
dc.contributor.authorUnci, Umit
dc.contributor.authorKaradeniz, Muhammed
dc.date.accessioned2025-01-21T16:43:47Z
dc.date.available2025-01-21T16:43:47Z
dc.date.issued2022
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackground. The coronary slow flow phenomenon (CSFP) is an atherosclerotic process that causes ischemia at the microvascular level. The CSFP may affect P wave durations, especially P wave peak time (PWPT), by microvascular ischemia, left ventricular diastolic dysfunction, and changes in the left atrial dimension. Therefore, in the present study, we aimed to assess PWPT in the CSFP. Method. One hundred and ninety-five patients were included in this single-center, retrospective study. Ninety patients were enrolled in the CSFP group and 105 patients in the control group. PWPT was defined as the duration between the beginning and peak of the p wave and obtained from the leads D-11 and V-I. Results. The mean age of the study population was 48.5 +/- 9.5, and 108 (55.3%) of the patients were female. We found PWPT was longer in the CSFP group than in the control group. Correlation analysis showed a positive correlation between PWPT in both leads (D-II, V-1) and left atrial anterior-posterior diameter, mean TIMI frame count (TFC), and E/e. A significant relationship was observed between mean TFC, E/e, EF, heart rate, and PWPT in lead D-11 (beta coefficient = 0.33, 95% CI 0.44-1.33, p < 0.001, beta coefficient = 0.23, 95% CI 0.25-1.85, p=0.01, beta coefficient = -0.140, 95% CI -1.04--0.53, p=0.03, and beta coefficient = -0.13, 95% CI -0.29--0.014, p=0.03, respectively) in multivariable linear analysis. Conclusion. In the present study, we found prolonged PWPT in patients with the CSFP and found a relationship between PWPT and mean TFC.
dc.identifier.doi10.1155/2022/4626701
dc.identifier.issn1368-5031
dc.identifier.issn1742-1241
dc.identifier.pmid35685567
dc.identifier.scopus2-s2.0-85131708242
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1155/2022/4626701
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25327
dc.identifier.volume2022
dc.identifier.wosWOS:000778914300008
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley-Hindawi
dc.relation.ispartofInternational Journal of Clinical Practice
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.titleProlonged P Wave Peak Time May Be a Sign of LV Diastolic Dysfunction in the Coronary Slow Flow Phenomenon
dc.typeArticle

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