Synthesis of aryl-substituted quinolines and tetrahydroquinolines through Suzuki-Miyaura coupling reactions

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dc.contributor.authorÖkten, Salih
dc.date.accessioned2020-06-25T18:34:00Z
dc.date.available2020-06-25T18:34:00Z
dc.date.issued2019
dc.departmentKırıkkale Üniversitesi
dc.descriptionOkten, Salih/0000-0001-9656-1803
dc.description.abstractThe synthesis and characterization of substituted (trifluoromethoxy, thiomethyl, and methoxy) phenyl quinolines is described. Dichlorobis(triphenylphosphine)palladiunn(II)-catalyzed Suzuki-Miyaura cross-coupling of 6-bromo- and 6,8-dibronno-1,2,3,4-tetrahydroquinolines, 5-bromo-8-methoxyquinoline, and 5,7-dibromo-8-methoxyquinoline with substituted phenylboronic acids affords the corresponding 6-aryl- (13a-d), 6,8-diaryl- (14a-c), 5-aryl- (15), and 5,7-diaryl- (16b, c) tetrahydroquinolines and quinolines in high yields (68%-82%). The structures of all the products are characterized by H-1 NMR, C-13 NMR, F-1(9) NMR, and Fourier transform infrared spectroscopy and by elemental analysis.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [112T394]en_US
dc.description.sponsorshipThe author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This study was supported by grants from the Scientific and Technological Research Council of Turkey (TUBITAK; project number: 112T394).en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1177/1747519819861389
dc.identifier.endpage280en_US
dc.identifier.issn1747-5198
dc.identifier.issn2047-6507
dc.identifier.issue7-8en_US
dc.identifier.scopus2-s2.0-85070482400
dc.identifier.scopusqualityQ3
dc.identifier.startpage274en_US
dc.identifier.urihttps://doi.org/10.1177/1747519819861389
dc.identifier.urihttps://hdl.handle.net/20.500.12587/7741
dc.identifier.volume43en_US
dc.identifier.wosWOS:000484663600009
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherSage Publications Ltden_US
dc.relation.ispartofJournal Of Chemical Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectaryl quinolinesen_US
dc.subjectnuclear magnetic resonance spectroscopyen_US
dc.subjectquinolinesen_US
dc.subjectsubstituted phenylsen_US
dc.subjectSuzuk-Miyaura cross-couplingen_US
dc.subjecttetrahydroquinolinesen_US
dc.titleSynthesis of aryl-substituted quinolines and tetrahydroquinolines through Suzuki-Miyaura coupling reactionsen_US
dc.typeArticle

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