The relationship between the helicobacter pylori seropositivity with systemic and local oxidative status and hyperemesis gravidarum: a pilot study

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dc.contributor.authorGoymen, Abdullah
dc.contributor.authorOzdurak, Ibrahim
dc.contributor.authorOzkaplan, Sukran Esra
dc.contributor.authorSimsek, Yavuz
dc.contributor.authorAvci, Fazil
dc.contributor.authorAkpak, Yasam Kemal
dc.date.accessioned2020-06-25T18:30:09Z
dc.date.available2020-06-25T18:30:09Z
dc.date.issued2018
dc.departmentKırıkkale Üniversitesi
dc.descriptionAkpak, Yasam Kemal/0000-0002-1699-8667
dc.description.abstractObjectives: The aim of study was to determine the helicobacter pylori (HP) seropositivity and oxidative parameters in serum and saliva of pregnant women with poor oral hygiene and hyperemesis gravidarum (HG).Methods: A case-control study was conducted involving 50 pregnant women in their first trimester of pregnancy. Twenty-five subjects had a diagnosis of HG, and remaining 25 were healthy pregnant women who served as control subjects were included. The groups were adjusted for age, parity and gestational week. All patients were subjected to the measurement of total oxidant status (TOS) and total antioxidant status in serum and saliva. Also HP seropositivity was investigated.Results: Serum TAS and TOS values were similar, although oxidative burden in saliva of women with HG were significantly higher than controls. HP seropositivity was found to be 24% in women with HG and 4% of controls.Conclusions: Our results suggest that significantly increased oxidative burden and slightly decreased antioxidative capacity of saliva may be involved in the pathogenesis of HG and this condition may be the result of HP infection which was found to be significantly more common in women with poor oral hygiene and HG.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1080/14767058.2017.1312328
dc.identifier.endpage1208en_US
dc.identifier.issn1476-7058
dc.identifier.issn1476-4954
dc.identifier.issue9en_US
dc.identifier.pmid28347201
dc.identifier.scopus2-s2.0-85017422153
dc.identifier.scopusqualityQ1
dc.identifier.startpage1204en_US
dc.identifier.urihttps://doi.org/10.1080/14767058.2017.1312328
dc.identifier.urihttps://hdl.handle.net/20.500.12587/7572
dc.identifier.volume31en_US
dc.identifier.wosWOS:000427919300017
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofJournal Of Maternal-Fetal & Neonatal Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHelicobacter pylorien_US
dc.subjecthyperemesis gravidarumen_US
dc.subjectseropositivityen_US
dc.subjectoxidative statusen_US
dc.subjectpregnancyen_US
dc.titleThe relationship between the helicobacter pylori seropositivity with systemic and local oxidative status and hyperemesis gravidarum: a pilot studyen_US
dc.typeArticle

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