Effects of vitamin C or vitamin E supplementation on Cadmium induced oxidative stress and anaemia in broilers

Basit Öğe Kaydı
dc.contributor.authorÇınar, Miyase
dc.contributor.authorYiğit, Ayşe Arzu
dc.contributor.authorEraslan, Gökhan
dc.date.accessioned2020-06-25T17:49:13Z
dc.date.available2020-06-25T17:49:13Z
dc.date.issued2010
dc.departmentKırıkkale Üniversitesi
dc.description.abstractThe aim of this study was to investigate the possible protective effects of vitamins C and E on lipid peroxidation (LPO), antioxidant systems and erythrocyte parameters in broilers chronically exposed to cadmium (Cd). One day old Ross broiler chickens were assigned to 4 equal groups (n = 12) according to the diet regimen; in the control group, birds received basal standard starter and grower diets, in Cd group they were supplemented with Cd (60 mg/kg) and in the 2 other groups, they were supplemented with Cd and with vitamin C (400 mg/kg) or with vitamin E (250 mg/kg) during the 42 clays long experimental period. The Cd exposition induced an oxidative stress characterised by the significant increase in plasma MDA concentrations coupled to significant decreases in enzyme antioxidant SOD (superoxide dismutase), CAT (catalase) and GSH-Px (glutathione peroxidase) activities and in plasma vitamin E, beta-carotene and uric acid concentrations. A moderate regenerative anaemia (low haemoglobinemia, erythrocyte name-ration and haematocrit associated with increase of the mean corpuscular volume) was also observed in the Cd group. Treatments with the vitamins C or E significantly reduced the lipid peroxidation but the antioxidant enzyme CAT and GSH-Px activities and vitamin E concentrations were significantly improved only with the vitamin E supplementation. Furthermore, the both types of vitamin supplementation, but particularly with ascorbate, have significantly increased the haemoglobinemia and the erythrocyte counts. These results clearly showed that vitamins C and E alleviate the oxidative effects of Cd at least partially and that the vitamin E exhibits more powerful antioxidant effects whereas vitamin C corrects more efficiently the anaemia.en_US
dc.description.sponsorshipKirikkale UniversityKirikkale University [05/10]en_US
dc.description.sponsorshipFinancial support for this project (Project No. 05/10) was provided by the Kirikkale University Research Fund.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.endpage454en_US
dc.identifier.issn0035-1555
dc.identifier.issn2258-0646
dc.identifier.issue10en_US
dc.identifier.scopus2-s2.0-78649825755
dc.identifier.scopusqualityN/A
dc.identifier.startpage449en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4665
dc.identifier.volume161en_US
dc.identifier.wosWOS:000284927100006
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherEcole Nationale Veterinaire Toulouseen_US
dc.relation.ispartofRevue De Medecine Veterinaire
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCadmiumen_US
dc.subjectbroileren_US
dc.subjectlipid peroxidationen_US
dc.subjectantioxidantsen_US
dc.subjectanaemiaen_US
dc.subjectvitamin Cen_US
dc.subjectvitamin Een_US
dc.titleEffects of vitamin C or vitamin E supplementation on Cadmium induced oxidative stress and anaemia in broilersen_US
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
Effects of vitamin C or vitamin E supplementation on Cadmium induced oxidative stress and anaemia in broilers.pdf
Boyut:
133.37 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin/Full Text
İndir

Koleksiyon

WOS İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
Makale Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu