Plasma lipocalin-2 levels in pregnancy
dc.contributor.author | Cesur, Semra | |
dc.contributor.author | Yucel, Aykan | |
dc.contributor.author | Noyan, Volkan | |
dc.contributor.author | Sagsoz, Nevin | |
dc.date.accessioned | 2020-06-25T18:06:53Z | |
dc.date.available | 2020-06-25T18:06:53Z | |
dc.date.issued | 2012 | |
dc.department | Kırıkkale Üniversitesi | |
dc.description | Yucel, Aykan/0000-0002-5888-692X | |
dc.description.abstract | Objective. To evaluate plasma levels of lipocalin-2, which is a novel adipokine associated with obesity and insulin resistance, in pregnant women. Design. Prospective casecontrol study. Setting. University hospital. Population. Pregnant women with pre-pregnancy body mass index >25kg/m2 (overweight; n=29) and body mass index <25kg/m2 (n=27), whose gestational ages were between 24 and 28weeks, as study groups and nonpregnant control women with body mass index <25kg/m2 (n=29). Methods. Plasma lipocalin-2 levels, fasting plasma glucose and fasting plasma insulin levels; homeostasis model assessment insulin resistance index and fasting plasma glucose/fasting plasma insulin ratio were measured for each subject. Main Outcome Measures. Comparisons among the groups and correlations for lipocalin-2 and the parameters of insulin resistance. Results. Plasma lipocalin-2 levels among the pregnant women were significantly higher than those of the control group (p<0.001 for both group comparisons). Lipocalin-2 levels were significantly higher in the group with pre-pregnancy body mass index >25kg/m2 compared with the group with pre-pregnancy body mass index <25kg/m2 (p=0.003). Lipocalin-2 levels were positively correlated with homeostasis model assessment insulin resistance index and fasting plasma insulin and negatively correlated with fasting plasma glucose/fasting plasma insulin ratio in both pregnant groups. Conclusions. Lipocalin-2 was found to be higher in pregnant women, especially when pre-pregnancy body mass index was >25kg/m2, and it was correlated with markers of insulin resistance. | en_US |
dc.identifier.citation | Cesur, S., Yucel, A., Noyan, V., & Sagsoz, N. (2012). Plasma lipocalin-2 levels in pregnancy. Acta obstetricia et gynecologica Scandinavica, 91(1), 112–116. | en_US |
dc.identifier.doi | 10.1111/j.1600-0412.2011.01158.x | |
dc.identifier.endpage | 116 | en_US |
dc.identifier.issn | 0001-6349 | |
dc.identifier.issue | 1 | en_US |
dc.identifier.pmid | 21504415 | |
dc.identifier.scopus | 2-s2.0-83455225427 | |
dc.identifier.scopusquality | Q1 | |
dc.identifier.startpage | 112 | en_US |
dc.identifier.uri | https://doi.org/10.1111/j.1600-0412.2011.01158.x | |
dc.identifier.uri | https://hdl.handle.net/20.500.12587/5391 | |
dc.identifier.volume | 91 | en_US |
dc.identifier.wos | WOS:000297922200018 | |
dc.identifier.wosquality | Q2 | |
dc.indekslendigikaynak | Web of Science | |
dc.indekslendigikaynak | Scopus | |
dc.indekslendigikaynak | PubMed | |
dc.language.iso | en | |
dc.publisher | Wiley-Blackwell | en_US |
dc.relation.ispartof | Acta Obstetricia Et Gynecologica Scandinavica | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Lipocalin-2 | en_US |
dc.subject | insulin resistance | en_US |
dc.subject | pregnancy | en_US |
dc.subject | overweight | en_US |
dc.title | Plasma lipocalin-2 levels in pregnancy | en_US |
dc.type | Article |
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