Drug allergy in tertiary care in Turkey: Results of a national survey. The ADAPT study: Adult drug allergy perception in Turkey

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dc.contributor.authorCelik, G. E.
dc.contributor.authorKarakaya, G.
dc.contributor.authorOzturk, A. B.
dc.contributor.authorGelincik, A.
dc.contributor.authorAbadoglu, O.
dc.contributor.authorSin, A.
dc.contributor.authorKalyoncu, F.
dc.date.accessioned2020-06-25T18:08:01Z
dc.date.available2020-06-25T18:08:01Z
dc.date.issued2014
dc.departmentKırıkkale Üniversitesi
dc.descriptionGOKSEL, Ozlem/0000-0003-1121-9967; Dursun, A. Berna/0000-0002-6337-6326; aydin, omur/0000-0002-3670-1728
dc.description.abstractBackground: No data are available on the incidence of drug hypersensitivity (DH) reactions in outpatient settings of tertiary allergy/immunology clinics. Our aims were to document the frequency of outpatient hospital admissions due to DH reactions to allergy/immunology clinics in adults and the management of these reactions in real life. We also investigated whether drug allergy affected social and medical behaviours of the patients. Methods: This multi-centre study was performed for one year with the participation of 11 out of 16 tertiary allergy/clinical immunology clinics in Turkey. The study group consisted of the patients with DH reactions. Results of a questionnaire including drug reactions and management were recorded. Results: Among 54,863 patients, 1000 patients with DH were enrolled with a median of 2.1% of all admissions. In real life conditions, the majority of approaches were performed for finding safe alternatives (65.5%; 1102 out of 1683) with 11.7% positivity. Diagnostic procedures were positive in 27% (154/581) of the patients. The majority of the patients had higher VAS scores for anxiety. A total of 250 subjects (25%) reported that they delayed some medical procedures because of DH. Conclusion: Our results documented the frequency of admissions due to DH reactions to allergy/clinical immunology clinics for the first time. Although physicians mostly preferred to perform drug tests in order to find safe alternatives, considering the fact that DH was confirmed in 27% of the patients, use of diagnostic tests should be encouraged, if no contraindication exists in order to avoid mislabelling patients as DH. (C) 2013 SEICAP. Published by Elsevier Espana, S.L.U. All rights reserved.en_US
dc.description.sponsorshipTurkish National Society of Allergy and Clinical Immunologyen_US
dc.description.sponsorshipThis study was supported by Turkish National Society of Allergy and Clinical Immunology.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1016/j.aller.2013.07.007
dc.identifier.endpage579en_US
dc.identifier.issn0301-0546
dc.identifier.issn1578-1267
dc.identifier.issue6en_US
dc.identifier.pmid24269184
dc.identifier.scopus2-s2.0-84926124794
dc.identifier.scopusqualityQ3
dc.identifier.startpage573en_US
dc.identifier.urihttps://doi.org/10.1016/j.aller.2013.07.007
dc.identifier.urihttps://hdl.handle.net/20.500.12587/5708
dc.identifier.volume42en_US
dc.identifier.wosWOS:000345555700011
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Espana Sluen_US
dc.relation.ispartofAllergologia Et Immunopathologia
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDrug allergyen_US
dc.subjectDrug hypersensitivityen_US
dc.subjectDrug provocation testsen_US
dc.subjectSkin prick testsen_US
dc.subjectGuidelinesen_US
dc.subjectEpidemiologyen_US
dc.titleDrug allergy in tertiary care in Turkey: Results of a national survey. The ADAPT study: Adult drug allergy perception in Turkeyen_US
dc.typeArticle

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