Peripheric and central olfactory measurements in patients with bipolar disorder

Basit Öğe Kaydı
dc.authoridBAYAR MULUK, NURAY/0000-0003-3602-9289
dc.contributor.authorKocakaya, Hanife
dc.contributor.authorBayar Muluk, Nuray
dc.contributor.authorBekin Sarikaya, Pelin Zeynep
dc.date.accessioned2025-01-21T16:43:23Z
dc.date.available2025-01-21T16:43:23Z
dc.date.issued2023
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackground Bipolar disorder (BD) is a mental health disorder. Purpose To investigate the peripheric and central olfactory measurements in patients with BD using magnetic resonance imaging (MRI). Material and Methods This study was conducted retrospectively. Group 1 consisted of 27 euthymic patients with BD (14 men, 13 women) and Group 2 consisted of 27 healthy controls (14 men, 13 women). Olfactory bulb (OB) volume and olfactory sulcus (OS) depth (peripheric), and corpus amygdala and insular gyrus area (central) measurements were performed using cranial MRI. Results OB volume and OS depth value of the bipolar group were lower than the control group, but there were no significant differences between the groups (P > 0.05). The corpus amygdala and left insular gyrus area of the bipolar group were significantly lower than those in the control group (P < 0.05). There were positive correlations between OB volumes and OS depths, the insular gyrus areas, and the corpus amygdala areas (P < 0.05). As the number of depressive episodes and duration of illness increased in bipolar patients, the depth of the sulcus decreased (P < 0.05). Conclusion In the present study a correlation was detected between OB volumes and the structures, known as emotional processing (e.g. insular gyrus area, corpus amygdala), and clinical features. Accordingly, new treatment techniques, such as olfactory training, may be considered an option in the treatment of such patients with BD.
dc.identifier.doi10.1177/02841851231179174
dc.identifier.endpage2602
dc.identifier.issn0284-1851
dc.identifier.issn1600-0455
dc.identifier.issue9
dc.identifier.pmid37312533
dc.identifier.scopus2-s2.0-85162668289
dc.identifier.scopusqualityQ3
dc.identifier.startpage2594
dc.identifier.urihttps://doi.org/10.1177/02841851231179174
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25257
dc.identifier.volume64
dc.identifier.wosWOS:001007324700001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSage Publications Ltd
dc.relation.ispartofActa Radiologica
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectBipolar disorder; cranial magnetic resonance imaging; olfactory bulb volume; olfactory sulcus depth; insular gyrus area; corpus amygdala area
dc.titlePeripheric and central olfactory measurements in patients with bipolar disorder
dc.typeArticle

Dosyalar

Koleksiyon

WOS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu