Retinal nerve fiber layer analysis in idiopathic intracranial hypertension

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dc.contributor.authorUysal, Tan Funda
dc.contributor.authorCengiz, Akarsu
dc.contributor.authorReyhan, Guülü
dc.contributor.authorHatice, Döner
dc.date.accessioned2020-06-25T17:43:33Z
dc.date.available2020-06-25T17:43:33Z
dc.date.issued2006
dc.description.abstractBackground: The chronic nature of idiopathic intracranial hypertension (IIH) represents a risk factor for progressive optic nerve damage and structural abnormalities of the retina. Aim: We measured the retinal nerve fiber layer (RNFL) thickness in patients followed with the diagnosis of IIH who had no or mild visual impairment to search for possible structural alterations in the retina for diagnostic and prognostic purposes. Settings and Design: Case-control prospective study. Materials and Methods: The study group consisted of 12 women followed and treated with the diagnosis of IIH in our clinic. The selection criteria were the, normal optic nerve, normal visual fields or mild visual field defects (Grade 1-3) by Humphrey perimeter. Randomly assigned, age-matched 12 healthy women were taken as the control group. Retinal nerve fiber layer thickness was evaluated with scanning laser polarimetry and both eyes were studied for each case in both groups. Statistical Analysis Used: Mann-Whitney U test. Results: The mean ages of the patient and the control groups were 34.58 +/- 4.2 and 34.42 +/- 5.7 years respectively (P=0.87). The mean duration of disease was 5.5 +/- 3 years. Some parameters related to RNFL thickness were found to differ significantly between patients with IIH and control subjects. Namely superior ratio (P=0.007), inferior ratio (P=0.039), superior-nasal ratio (P=0.025), maximum modulation (P=0.01) and symmetry (P=0.006) were lower in the patient group than controls. Conclusion: Scanning laser polarimetry might be a good adjunct for determining possible structural affects of IIH on the retina in patients with no or mild visual impairment.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.endpage172en_US
dc.identifier.issn0028-3886
dc.identifier.issue2en_US
dc.identifier.pmid16804262
dc.identifier.scopus2-s2.0-33745753020
dc.identifier.scopusqualityQ3
dc.identifier.startpage168en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3784
dc.identifier.volume54en_US
dc.identifier.wosWOS:000239211900011
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherNeurol Soc Indiaen_US
dc.relation.ispartofNeurology India
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectidiopathic intracranial hypertensionen_US
dc.subjectretinal nerve fiber layer thicknessen_US
dc.subjectscanning laser polarimetryen_US
dc.titleRetinal nerve fiber layer analysis in idiopathic intracranial hypertensionen_US
dc.typeArticle

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