Left atrial function index and left atrial electromechanical functions in anxiety disorders

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dc.authoridTuran, Yasar/0000-0002-2796-899X
dc.authoridOzturk, Selcuk/0000-0002-3426-1212
dc.authoridErdogan, Mehmet/0000-0002-2747-3823
dc.contributor.authorOzturk, Hayriye Mihrimah
dc.contributor.authorErdogan, Mehmet
dc.contributor.authorTuran, Yasar
dc.contributor.authorCelik, Ibrahim Etem
dc.contributor.authorOzturk, Selcuk
dc.date.accessioned2025-01-21T16:42:19Z
dc.date.available2025-01-21T16:42:19Z
dc.date.issued2024
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackgroundThere is a close linkage between anxiety disorders (ADs), and development of cardiovascular disease (CVD) and atrial fibrillation (AF). We aimed to investigate left atrial function index (LAFI) and its components, LA mechanical functions and atrial conduction times in AD patients and age- and gender-matched control group patients for the first time in the literature.MethodsA total of 48 AD patients and 33 healthy subjects were enrolled to the study prospectively. Echocardiographic parameters including two-dimensional conventional echocardiography, diastolic functions, LA mechanical functions, LAFI, atrial conduction times and atrial electromechanical delay (AEMD) were calculated.ResultsThe velocity-time integral of the LV outflow tract (LVOT-VTI), LAFI and LA conduit volume were significantly lower in AD patients. Atrial electromechanical coupling as established from lateral mitral annulus (PA lateral) was significantly higher in AD group than control group. Inter-AEMD and left intra-AEMD were also higher in AD group compared to control group. Age, gender, body surface area (BSA), conduit volume, LVOT-VTI and LAFI were significant factors associated with AD in univariate analysis. However, only BSA and LVOT-VTI (Odds ratio [OR]: 0.79, 95 CI%: 0.66-0.95, p = 0.013) were independently associated with AD in multivariate analysis. Age, gender, conduit volume and LAFI (OR: 0.25, 95 CI%: 0.03-2.12, p = 0.204) were not found to be independent associates of AD.ConclusionLAFI is impaired in patients suffering from AD compared to their age- and gender-matched counterparts but this impairment originates from lower levels of LVOT-VTI calculations in AD patients. Thus, LVOT-VTI, but not LAFI, is independently associated with AD.
dc.identifier.doi10.1080/00015385.2024.2336345
dc.identifier.endpage693
dc.identifier.issn0001-5385
dc.identifier.issn1784-973X
dc.identifier.issue6
dc.identifier.pmid38572756
dc.identifier.scopus2-s2.0-85189988970
dc.identifier.scopusqualityQ3
dc.identifier.startpage685
dc.identifier.urihttps://doi.org/10.1080/00015385.2024.2336345
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25052
dc.identifier.volume79
dc.identifier.wosWOS:001196783300001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Ltd
dc.relation.ispartofActa Cardiologica
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectAnxiety disorders; left atrial function index; left atrium mechanical functions; left ventricular outflow tract velocity time integral; tissue doppler echocardiography
dc.titleLeft atrial function index and left atrial electromechanical functions in anxiety disorders
dc.typeArticle

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