Analysis of Borrelia burgdorferi antibody seroprevalence in patients with Behçet's disease using 3 different serological assays

dc.contributor.authorAyaşlıoğlu, Ergin
dc.contributor.authorErkek, Emel
dc.contributor.authorKaygusuz, Sedat
dc.contributor.authorKılıç, Dilek
dc.contributor.authorİnal, Ali
dc.contributor.authorKeskin, Göksal
dc.date.accessioned2021-01-14T18:16:15Z
dc.date.available2021-01-14T18:16:15Z
dc.date.issued2004
dc.description.abstractAbstract: Behçet's disease is a chronic multisystemic inflammatory vasculitis of unknown etiology. Various infectious agents have been implicated as potential triggering factors in the pathogenesis of the disease. The present study was designed to evaluate the seroprevalence of Borrelia burgdorferi antibodies in Turkish patients with Behçet's disease. For this purpose, 90 consecutive patients with Behçet's disease and 50 healthy individuals were enrolled into a prospective study. The IgM and IgG antibodies to B. burgdorferi in sera were determined by 3 different serological techniques, namely indirect immunofluorescence assay (IFA), enzyme linked immunosorbent assay (ELISA) and Western blotting (WB). Although there was a tendency in the patient group toward a higher seropositivity rate using the ELISA and WB tests, statistical analysis revealed no difference in antibody prevalence between the patient and control groups for each technique performed (P >0.05 for all 3 assays). The findings of the present study do not support a potential role for B. burgdorferi in the etiopathogenesis of Behçet's disease, at least in the geographical region of central Anatolia.en_US
dc.identifier.citationAyaşlıoğlu E., Erkek E., Kaygusuz S., Kılıç D., İnal A., Keskin G. (2004). Analysis of Borrelia burgdorferi antibody seroprevalence in patients with Behçet's disease using 3 different serological assays. Turkish Journal of Medical Sciences, 34(6), 375 - 378.en_US
dc.identifier.endpage378en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-11244253218
dc.identifier.scopusqualityQ1
dc.identifier.startpage375en_US
dc.identifier.trdizinid52823
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TlRJNE1qTXo
dc.identifier.urihttps://hdl.handle.net/20.500.12587/13056
dc.identifier.volume34en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofTurkish Journal of Medical Sciences
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCerrahien_US
dc.titleAnalysis of Borrelia burgdorferi antibody seroprevalence in patients with Behçet's disease using 3 different serological assaysen_US
dc.typeArticle

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