Evaluation of Advanced Platelet Rich Fibrin (A-PRF) on Bone Healing. Is It Better than Old Version? A Histological Animal Study

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dc.contributor.authorTitirinli, Kubra
dc.contributor.authorTekin, Umut
dc.contributor.authorAtil, Fethi
dc.contributor.authorOnder, M. Ercument
dc.contributor.authorSenguven, Burcu
dc.contributor.authorOzgul, Ozkan
dc.contributor.authorKocyigit, Ismail Doruk
dc.date.accessioned2020-06-25T18:22:59Z
dc.date.available2020-06-25T18:22:59Z
dc.date.issued2017
dc.departmentKırıkkale Üniversitesi
dc.descriptionOnder, M Ercument/0000-0002-1488-616X
dc.description.abstractObjective: This study aims to evaluate the effect of fibrin, which is formed with an alteration to the standard PRF centrifugation protocol, on the bone formation. The study additionally aims to assess cell-distribution, and to evaluate the effects of alterations in the speed and duration of centrifugation on the changes in cell-distribution and the formation of hard tissue, by making histological investigations. Materials and methods: Ten New Zealand rabbits were used in this experimental animal study. PRF (2700 rpm, 12 min) and APRF (1500 rpm, 14 min) were placed in the standard bone defects that formed in the right corpus of the mandible randomly. No additional material was placed in the left mandible defect, as a control group. Rabbits were sacrificed after two months, the histological evaluation was performed. Results: There were no marked differences between groups in regard to the quantity of bone formation and bone quality. The quantities of new bone formation were (mean) 56.9%, 55%, 42.5%. Discussion: It may be considered that PRF and its variations have positive effects on the new bone tissue and cell number, and may lead to more rapid ossification compared to the unprocessed bone defects.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1166/jbt.2017.1592
dc.identifier.endpage483en_US
dc.identifier.issn2157-9083
dc.identifier.issn2157-9091
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-85015639173
dc.identifier.scopusqualityN/A
dc.identifier.startpage478en_US
dc.identifier.urihttps://doi.org/10.1166/jbt.2017.1592
dc.identifier.urihttps://hdl.handle.net/20.500.12587/6976
dc.identifier.volume7en_US
dc.identifier.wosWOS:000398930300006
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherAmer Scientific Publishersen_US
dc.relation.ispartofJournal Of Biomaterials And Tissue Engineering
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPRFen_US
dc.subjectAPRFen_US
dc.subjectBone Formationen_US
dc.titleEvaluation of Advanced Platelet Rich Fibrin (A-PRF) on Bone Healing. Is It Better than Old Version? A Histological Animal Studyen_US
dc.typeArticle

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