A Comparison of Various Vascularization-Perfusion Venous Nerve Grafts with Conventional Nerve Grafts in Rats

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dc.authoridErdem Ozdamar, Sevim/0000-0001-9348-6457
dc.authoridSURUCU, HUSEYIN SELCUK/0000-0002-9244-4236
dc.authoridDemirci, Mehmet/0000-0002-7316-3877
dc.contributor.authorVargel, Ibrahim
dc.contributor.authorDemirci, Mehmet
dc.contributor.authorErdem, Sevim
dc.contributor.authorFirat, Pinar
dc.contributor.authorSurucu, H. Selcuk
dc.contributor.authorTan, Ersin
dc.contributor.authorKecik, Abdullah
dc.date.accessioned2025-01-21T16:34:56Z
dc.date.available2025-01-21T16:34:56Z
dc.date.issued2009
dc.departmentKırıkkale Üniversitesi
dc.description.abstractPeripheral nerves with defective segments can only be repaired using nerve grafts. Among the various nerve graft options, the outcome of vascularized grafts has been shown to be better, especially when used in the hypovascular and scarred recipient bed. The purpose of this study was to compare the regeneration capacities of various types of venous nerve grafts in a rat model. Forty adult male Wistar albino rats were divided Into four groups. A 2-cm-long segment of femoral sheath was isolated from the surrounding tissue without disturbing the unity, of the femoral sheath contents. Four different nerve graft models were applied: flow-through venous, arterialized venous, prefabricated venous, and conventional nerve graft (control). All nerve grafts were closed with silicone sheets. These neurovascular segments were reopened in postoperative week 10 to determine the viability of the grafted nerves and to assess the degree of nerve healing. Histopathologic C examinations, morphometric analysis, and electrophysiological measurements were performed. The degree of nerve healing in the flow-through venous nerve grafts was similar to that observed in the arterialized nerve grafts. Prefabricated flow-through venous grafts were not as successful as flow-through Venous grafts or arterialized nerve grafts. All of the vascularized nerve grafts showed better results than the conventional nerve grafts.
dc.identifier.doi10.1055/s-0029-1223852
dc.identifier.endpage437
dc.identifier.issn0743-684X
dc.identifier.issn1098-8947
dc.identifier.issue7
dc.identifier.pmid19472105
dc.identifier.startpage425
dc.identifier.urihttps://doi.org/10.1055/s-0029-1223852
dc.identifier.urihttps://hdl.handle.net/20.500.12587/24040
dc.identifier.volume25
dc.identifier.wosWOS:000269719700005
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherThieme Medical Publ Inc
dc.relation.ispartofJournal of Reconstructive Microsurgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectVenous nerve graft; peripheral nerve healing; vascularized nerve graft model
dc.titleA Comparison of Various Vascularization-Perfusion Venous Nerve Grafts with Conventional Nerve Grafts in Rats
dc.typeArticle

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