Mode of delivery changes oxidative and antioxidative properties of human milk: a prospective controlled clinical investigation

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dc.contributor.authorSimsek, Yavuz
dc.contributor.authorKarabiyik, Pinar
dc.contributor.authorPolat, Kubra
dc.contributor.authorDuran, Zeynep
dc.contributor.authorPolat, Alaaddin
dc.date.accessioned2020-06-25T18:13:23Z
dc.date.available2020-06-25T18:13:23Z
dc.date.issued2015
dc.departmentKırıkkale Üniversitesi
dc.descriptionyoldas, zeynep rumeysa/0000-0002-5608-9003
dc.description.abstractObjective: To evaluate the influence of delivery mode on oxidative stress in human breast milk. Methods: Thirty-three women who delivered by vaginal birth and 55 women who underwent cesarean section (CS) were included in this study. Colostral samples were collected on the second day after delivery. Total antioxidative status (TAS), total oxidative status (TOS), oxidative stress index (OSI), malonyldialdehyde (MDA), and glutathione peroxidase (GSH-Px) levels were determined and compared. Results: Colostrum TAS was significantly higher in women of vaginal birth, than in women with CS (p<0.001). Milk TOS and OSI were found to be significantly increased in women with CS under general anesthesia. A marked increase in colostral GSH-Px levels after vaginal delivery was also noticed (p<0.001). Conclusion: This study revealed that vaginal birth is associated with decreased oxidative stress in colostrum than CS, which suggest that mode of delivery plays an important role in the antioxidative production of breast milk.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [2209]en_US
dc.description.sponsorshipThis study has been funded by The Scientific and Technological Research Council of Turkey (TUBITAK) with a project number of 2209.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.3109/14767058.2014.932345
dc.identifier.endpage738en_US
dc.identifier.issn1476-7058
dc.identifier.issn1476-4954
dc.identifier.issue6en_US
dc.identifier.pmid24903065
dc.identifier.scopus2-s2.0-84929603748
dc.identifier.scopusqualityQ1
dc.identifier.startpage734en_US
dc.identifier.urihttps://doi.org/10.3109/14767058.2014.932345
dc.identifier.urihttps://hdl.handle.net/20.500.12587/6188
dc.identifier.volume28en_US
dc.identifier.wosWOS:000354606400024
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofJournal Of Maternal-Fetal & Neonatal Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBreast milken_US
dc.subjectcesarean sectionen_US
dc.subjectoxidative stressen_US
dc.subjectparturitionen_US
dc.titleMode of delivery changes oxidative and antioxidative properties of human milk: a prospective controlled clinical investigationen_US
dc.typeArticle

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