Corneal endothelial changes following a single session of selective laser trabeculoplasty for pseudoexfoliative glaucoma

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dc.contributor.authorOrnek, Nurgul
dc.contributor.authorOrnek, Kemal
dc.date.accessioned2020-06-25T18:29:20Z
dc.date.available2020-06-25T18:29:20Z
dc.date.issued2018
dc.departmentKırıkkale Üniversitesi
dc.description.abstractPurposeTo evaluate corneal endothelial cell parameters after a single session of selective laser trabeculoplasty (SLT) in pseudoexfoliative glaucoma (PEG) patients.MethodsCorneal endothelial cell parameters of 18 PEG patients were compared with 18 healthy subjects following SLT treatment. All patients underwent SLT treatment to 180 degrees of inferior trabecular meshwork. Corneal measurements were performed using specular microscopy (Noncon Robo SP8000, Konan Medical, Hyogo, Japan). Endothelial cell density (ECD), hexagonal cell ratio (HEX), coefficient of variation (CV) of the corneal endothelial cell layer and central corneal thickness of the patients were measured at each visit.ResultsThere was a statistically significant decrease in ECD (p=0.004) and a statistically significant increase in CV (p=0.041) at superior cornea 1week after SLT. They returned to pre-SLT values at 1month. One hour post-SLT HEX of inferior cornea was statistically significantly reduced (p=0.01). At central cornea, there was a significant increase in HEX after 1week (p=0.001). Post-SLT IOP showed a significant positive correlation with CV and significant negative correlation with HEX at superior and inferior cornea. There was no correlation between total laser energy used and endothelial cell parameters.ConclusionEffect of a single session ofSLT on corneal endothelium of PEG patients appears to be transient, and superior cornea was more affected than central and inferior cornea. All parameters returned to pre-SLT values at 1month after treatment.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1007/s10792-017-0730-0
dc.identifier.endpage2333en_US
dc.identifier.issn0165-5701
dc.identifier.issn1573-2630
dc.identifier.issue6en_US
dc.identifier.pmid29030797
dc.identifier.scopus2-s2.0-85031426388
dc.identifier.scopusqualityQ2
dc.identifier.startpage2327en_US
dc.identifier.urihttps://doi.org/10.1007/s10792-017-0730-0
dc.identifier.urihttps://hdl.handle.net/20.500.12587/7241
dc.identifier.volume38en_US
dc.identifier.wosWOS:000451676200011
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringeren_US
dc.relation.ispartofInternational Ophthalmology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSelective laser trabeculoplastyen_US
dc.subjectPseudoexfoliative glaucomaen_US
dc.subjectCorneal endotheliumen_US
dc.subjectCentral corneal thicknessen_US
dc.subjectIntraocular pressureen_US
dc.titleCorneal endothelial changes following a single session of selective laser trabeculoplasty for pseudoexfoliative glaucomaen_US
dc.typeArticle

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