Thyroid Autoimmunity may Affect Mean Platelet Volume
dc.authorid | KALAN SARI, ISILAY/0000-0002-0391-7848 | |
dc.contributor.author | Sari, Isilay Kalan | |
dc.contributor.author | Arikan, Senay | |
dc.contributor.author | Yavuz, Seyma | |
dc.contributor.author | Carlioglu, Ayse | |
dc.date.accessioned | 2025-01-21T16:55:29Z | |
dc.date.available | 2025-01-21T16:55:29Z | |
dc.date.issued | 2022 | |
dc.department | Kırıkkale Üniversitesi | |
dc.description.abstract | Objective: Mean platelet volume (MPV) has been associated with autoimmune diseases and is considered a potentially useful parameter to assess platelet activity and subclinical inflammation. In the present study, we aimed to investigate the effects of thyroid autoimmunity on MPV. Methods: 84 patients with newly diagnosed Hashimoto's thyroiditis (HT), including 44 euthyroid (EHT, mean age 41.4 +/- 10.8 years) and 40 hypothyroid (HHT, mean age 44.6 +/- 13.2 years) patients, 61 patients with newly diagnosed Graves' disease (GD, mean age 42.8 +/- 12.4 years) and 57 euthyroid control subjects (age-matched 46.4 +/- 11.6 years) were included in the study. Patients were not taking antithyroid medication or levothyroxine. Thyroid hormones and platelet parameters were determined in all study participants. Results: The MPV of the patients was significantly higher than that of the control group (p:0.008). There was no association between MPV and age, sex, or TSH (p:0.06, p:0.4, and p:0.9, respectively). MPV increased in chronic autoimmune thyroid disease regardless of age, sex, and TSH. Conclusion: Our results suggest that autoimmunity, rather than thyroid hormone levels, affects MPV in GD and HT. | |
dc.identifier.doi | 10.12996/gmj.2022.76 | |
dc.identifier.endpage | 340 | |
dc.identifier.issn | 2147-2092 | |
dc.identifier.issue | 4 | |
dc.identifier.scopus | 2-s2.0-85140309469 | |
dc.identifier.scopusquality | Q4 | |
dc.identifier.startpage | 337 | |
dc.identifier.uri | https://doi.org/10.12996/gmj.2022.76 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12587/25792 | |
dc.identifier.volume | 33 | |
dc.identifier.wos | WOS:000863207700004 | |
dc.identifier.wosquality | N/A | |
dc.indekslendigikaynak | Web of Science | |
dc.indekslendigikaynak | Scopus | |
dc.language.iso | en | |
dc.publisher | Gazi Univ, Fac Med | |
dc.relation.ispartof | Gazi Medical Journal | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.snmz | KA_20241229 | |
dc.subject | Graves' disease; hashimoto's thyroiditis; mean platelet volume; platelets; thyroid; thyroid-stimulating hormone | |
dc.title | Thyroid Autoimmunity may Affect Mean Platelet Volume | |
dc.title.alternative | Tiroid Otoimmünitesi Ortalama Trombosit Hacmini Etkileyebilir | |
dc.type | Article |