Thyroid Autoimmunity may Affect Mean Platelet Volume

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dc.authoridKALAN SARI, ISILAY/0000-0002-0391-7848
dc.contributor.authorSari, Isilay Kalan
dc.contributor.authorArikan, Senay
dc.contributor.authorYavuz, Seyma
dc.contributor.authorCarlioglu, Ayse
dc.date.accessioned2025-01-21T16:55:29Z
dc.date.available2025-01-21T16:55:29Z
dc.date.issued2022
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjective: Mean platelet volume (MPV) has been associated with autoimmune diseases and is considered a potentially useful parameter to assess platelet activity and subclinical inflammation. In the present study, we aimed to investigate the effects of thyroid autoimmunity on MPV. Methods: 84 patients with newly diagnosed Hashimoto's thyroiditis (HT), including 44 euthyroid (EHT, mean age 41.4 +/- 10.8 years) and 40 hypothyroid (HHT, mean age 44.6 +/- 13.2 years) patients, 61 patients with newly diagnosed Graves' disease (GD, mean age 42.8 +/- 12.4 years) and 57 euthyroid control subjects (age-matched 46.4 +/- 11.6 years) were included in the study. Patients were not taking antithyroid medication or levothyroxine. Thyroid hormones and platelet parameters were determined in all study participants. Results: The MPV of the patients was significantly higher than that of the control group (p:0.008). There was no association between MPV and age, sex, or TSH (p:0.06, p:0.4, and p:0.9, respectively). MPV increased in chronic autoimmune thyroid disease regardless of age, sex, and TSH. Conclusion: Our results suggest that autoimmunity, rather than thyroid hormone levels, affects MPV in GD and HT.
dc.identifier.doi10.12996/gmj.2022.76
dc.identifier.endpage340
dc.identifier.issn2147-2092
dc.identifier.issue4
dc.identifier.scopus2-s2.0-85140309469
dc.identifier.scopusqualityQ4
dc.identifier.startpage337
dc.identifier.urihttps://doi.org/10.12996/gmj.2022.76
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25792
dc.identifier.volume33
dc.identifier.wosWOS:000863207700004
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherGazi Univ, Fac Med
dc.relation.ispartofGazi Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectGraves' disease; hashimoto's thyroiditis; mean platelet volume; platelets; thyroid; thyroid-stimulating hormone
dc.titleThyroid Autoimmunity may Affect Mean Platelet Volume
dc.title.alternativeTiroid Otoimmünitesi Ortalama Trombosit Hacmini Etkileyebilir
dc.typeArticle

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