Anesthetic effectiveness of topical levobupivacaine 0.75% versus topical proparacaine 0.5% for intravitreal injections

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dc.contributor.authorÖrnek N.
dc.contributor.authorApan A.
dc.contributor.authorÖrnek K.
dc.contributor.authorGünay F.
dc.date.accessioned2020-06-25T15:17:28Z
dc.date.available2020-06-25T15:17:28Z
dc.date.issued2014
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackground and Purpose: Today no method of topical anesthesia for intravitreal injection administration has been proven to make the patient comfortable yet. We compared the efficacy of topical levobupivacaine 0.75% and proparacaine 0.5% in patients undergoing intravitreal injections. Materials and Methods: A prospective, randomized study comparing two agents for topical anesthesia in intravitreal injections. Ninety-six consecutive patients were enrolled into two groups to receive either topical levobupivacaine 0.75% (n=48) or proparacaine 0.5% (n=48). Patients were asked to score their pain using a visual analog scale (VAS) immediately following the injection. The average of these scores was used as the primary outcome. The surgeon performing the procedure scored his perception of the patients? pain using the Wong-Baker FACES scale. Results: Mean VAS pain scores for two groups were found to be 44.77 ± 16.42 and 34.18 ± 14.83, respectively. Mean VAS pain score in the proparacaine group was significantly lower than that in the levobupivacaine group (P= 0.003). Mean Wong-Baker FACES scores for the two groups were 1.08 ± 0.49 and 1.10 ± 0.30, respectively. There was no statistically significant difference between levobupivacaine and proparacaine groups (P=0.824). Conclusions: Topical proparacaine 0.5% was more effective in preventing pain during intravitreal injections.en_US
dc.identifier.doi10.4103/1658-354X.130713
dc.identifier.endpage201en_US
dc.identifier.issn1658354X
dc.identifier.issue2en_US
dc.identifier.pmid24843332
dc.identifier.scopus2-s2.0-84899758491
dc.identifier.scopusqualityQ3
dc.identifier.startpage198en_US
dc.identifier.urihttps://doi.org/10.4103/1658-354X.130713
dc.identifier.urihttps://hdl.handle.net/20.500.12587/2381
dc.identifier.volume8en_US
dc.identifier.wosWOS:000219136100010
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherMedknow Publicationsen_US
dc.relation.ispartofSaudi Journal of Anaesthesia
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnesthetic effectivenessen_US
dc.subjectintravitreal injectionsen_US
dc.subjecttopical levobupivacaineen_US
dc.subjecttopical proparacaineen_US
dc.titleAnesthetic effectiveness of topical levobupivacaine 0.75% versus topical proparacaine 0.5% for intravitreal injectionsen_US
dc.typeArticle

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