Novel multifunctional colloidal carbohydrate nanofiber electrolytes with excellent conductivity and responses to bone cancer cells

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dc.contributor.authorGökmen, Fatma Özge
dc.contributor.authorRzayev, Zakir M. O.
dc.contributor.authorSalimi, Kouroush
dc.contributor.authorBunyatova, Ulviya
dc.contributor.authorAcar, Selim
dc.contributor.authorSalamov, Bahtiyar
dc.contributor.authorTürk, Mustafa
dc.date.accessioned2020-06-25T18:12:40Z
dc.date.available2020-06-25T18:12:40Z
dc.date.issued2015
dc.departmentKırıkkale Üniversitesi
dc.descriptionGokmen, Fatma Ozge/0000-0002-5548-8790
dc.description.abstractThis work presents a new approach to fabricating novel polymer nanofiber composites (NFCs) from water solution blends of PVA (hydrolyzed 89%)/ODA-MMT and Na-CMC/ODA-MMT nanocomposites as well as their folic acid (FA) incorporated modifications (NC-3-FA and NC-4-FA) through green electrospinning nanotechnology. The chemical and physical structures and surface morphology of the nanofiber composites were confirmed. Significant improvements in nanofiber morphology and size distribution of the NFC-3-FA and NFC-4-FA nanofibers with lower average means 110 and 113 nm compared with those of NFC-1/NFC-2 nanofibers (270 and 323 nm) were observed. The structural elements of polymer NFCs, particularly loaded partner NC-2, plays an important role in chemical and physical interfacial interactions, phase separation processing and enables the formation of nanofibers with unique morphology and excellent conductivity (NFC-3-FA 3.25 x 10(-9) S/cm and NFC-4-FA 8.33 x 10(-4) S/cm). This is attributed to the higher surface contact areas and multifunctional self-assembled supramacromolecular nanostructures of amorphous colloidal electrolytes. The anticancer activity of FA-containing nanofibers against osteocarcinoma cells were evaluated by cytotoxicity, apoptotic and necrotic analysis methods. (C) 2015 Elsevier Ltd. All rights reserved.en_US
dc.description.sponsorshipTurkish Scientific and Technological Research Council (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [TBAG-HD/249, BIDEB-PD/2218]en_US
dc.description.sponsorshipThe authors would like to acknowledge the Turkish Scientific and Technological Research Council (TUBITAK) for the financial support of this work through postdoctoral projects TBAG-HD/249 and BIDEB-PD/2218.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1016/j.carbpol.2015.06.106
dc.identifier.endpage636en_US
dc.identifier.issn0144-8617
dc.identifier.issn1879-1344
dc.identifier.pmid26344321
dc.identifier.scopus2-s2.0-84938919343
dc.identifier.scopusqualityQ1
dc.identifier.startpage624en_US
dc.identifier.urihttps://doi.org/10.1016/j.carbpol.2015.06.106
dc.identifier.urihttps://hdl.handle.net/20.500.12587/6001
dc.identifier.volume133en_US
dc.identifier.wosWOS:000361920900075
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Sci Ltden_US
dc.relation.ispartofCarbohydrate Polymers
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPVAen_US
dc.subjectNa-CMCen_US
dc.subjectOrganoclayen_US
dc.subjectNanocompositesen_US
dc.subjectNanofibersen_US
dc.subjectElectrospinningen_US
dc.subjectStructure-property relationshipsen_US
dc.subjectMorphologyen_US
dc.subjectConductivityen_US
dc.subjectBone cancer cellsen_US
dc.titleNovel multifunctional colloidal carbohydrate nanofiber electrolytes with excellent conductivity and responses to bone cancer cellsen_US
dc.typeArticle

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