Alterations of intracorporeal structures in patients with erectile dysfunction

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dc.contributor.authorYaman, O
dc.contributor.authorYilmaz, E
dc.contributor.authorBozlu, M
dc.contributor.authorAnafarta, K
dc.date.accessioned2020-06-25T17:35:44Z
dc.date.available2020-06-25T17:35:44Z
dc.date.issued2003
dc.departmentKırıkkale Üniversitesi
dc.descriptionBozlu, Murat/0000-0002-8624-0149; Yaman, Onder/0000-0002-1587-0688
dc.description.abstractObjective: We sought to quantify intracavernosal smooth muscle content (SMC), endothelial cells (EC) and elastic fibres (EF) in both potent and impotent men. We compare the results in impotent men with regard to patient age, aetiology of impotence, presence or absence of diabetes mellitus and smoking. Patients and Methods: Seventy penile biopsies were taken from 10 potent patients with congenital penile curvature (age 1724 years, mean: 21 +/- 1.16) and from 60 impotent patients (age 28-64 years, mean: 46 +/- 7.64). Biopsies were stained immunohistochemically to quantify the percentage of SMC by anti-desmin and anti-SMA, anti-CD-34 for EC and Verhoeff's histochemical staining for EF. Statistical analyses were performed by using one-way Anova after square root transformation. Results: We observed a statistically significant difference in the amounts of corporeal SMC, EC and EF with regard to the following subgroups: potent versus impotent men; men with arterial aetiology versus veno-occlusive aetiology; men under the age of 45 versus men over the age of 45; patients with diabetes mellitus versus non-diabetes mellitus, and smokers versus non-smokers. Conclusion: Quantification of intracavernosal structures appears to be important for either understanding the mechanism of impotence or deciding the appropriate treatment. Copyright (C) 2003 S. Karger AG, Basel.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1159/000071101
dc.identifier.endpage90en_US
dc.identifier.issn0042-1138
dc.identifier.issue1en_US
dc.identifier.pmid12845268
dc.identifier.scopus2-s2.0-0037971655
dc.identifier.scopusqualityQ2
dc.identifier.startpage87en_US
dc.identifier.urihttps://doi.org/10.1159/000071101
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3195
dc.identifier.volume71en_US
dc.identifier.wosWOS:000184179000018
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherKargeren_US
dc.relation.ispartofUrologia Internationalis
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectimpotenceen_US
dc.subjectsmooth muscle cellsen_US
dc.subjectendotheliumen_US
dc.subjectelastic fibresen_US
dc.titleAlterations of intracorporeal structures in patients with erectile dysfunctionen_US
dc.typeArticle

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