Evaluation of renal arterial resistive index in patients with extrahepatic cholestasis

Basit Öğe Kaydı
dc.authoridDUSUNCELI, IBRAHIMHALIL/0000-0001-5381-0275
dc.authoridBAYAV, Murat/0000-0002-8210-4182
dc.contributor.authorSargin, Z. Gok
dc.contributor.authorBayav, M.
dc.contributor.authorDusunceli, I.
dc.contributor.authorCelik, U.
dc.contributor.authorUstundag, Y.
dc.date.accessioned2025-01-21T16:40:42Z
dc.date.available2025-01-21T16:40:42Z
dc.date.issued2023
dc.departmentKırıkkale Üniversitesi
dc.description.abstractOBJECTIVE: Biliary obstruction has been shown to cause acute renal failure. The Renal Resistive Index (RRI) has been recognized to be an important index for evaluating changes in renal plasma flow and renal damage in cholestatic patients. We aimed to investigate the effects of cholestasis on renal hemodynamics in patients with extrahepatic cholestasis by RRI.PATIENTS AND METHODS: The prospective study included patients with extrahepatic cholestasis due to benign biliary stricture, choledocholithiasis, or periampullary tumor between January 1, 2022, and December 31, 2022. Renal and liver function tests, as well as renal doppler ultrasound for RRIs, were conducted before and after cholestasis treatment.RESULTS: Patients who experienced cholestasis resolution after treatment showed lower cholestasis enzymes and bilirubin values and higher glomerular filtration rates compared to pre-treatment values. RRI values significantly decreased in patients with resolved cholestasis compared to pre-treatment levels (p=0.009). Patients with malignant cholestasis had higher RRI values than those with benign cholestasis (p=0.006). Bilirubin levels were higher (p=0.001), and glomerular filtration rates were lower (p=0.046) in patients with malignant cholestasis compared to those with benign cholestasis.CONCLUSIONS: Acute renal injury in cholestatic patients can be demonstrated non-invasively by RRI and is reversible once cholestasis has resolved. Patients with benign cholestasis had lower RRI values than those with cholestasis due to periampullary tumors.
dc.identifier.endpage10445
dc.identifier.issn1128-3602
dc.identifier.issue21
dc.identifier.pmid37975367
dc.identifier.scopus2-s2.0-85177990581
dc.identifier.scopusqualityQ2
dc.identifier.startpage10438
dc.identifier.urihttps://hdl.handle.net/20.500.12587/24750
dc.identifier.volume27
dc.identifier.wosWOS:001110624200005
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherVerduci Publisher
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectRenal arterial resistive index; Benign extrahepatic cholestasis; Malign extrahepatic cholestasis; Acute re-nal injury
dc.titleEvaluation of renal arterial resistive index in patients with extrahepatic cholestasis
dc.typeArticle

Dosyalar

Koleksiyon

WOS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu